ID A0A1G1ME81_9BACT Unreviewed; 479 AA.
AC A0A1G1ME81;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Ribonuclease G {ECO:0000256|ARBA:ARBA00017719};
GN ORFNames=A2166_02900 {ECO:0000313|EMBL:OGX15695.1};
OS Omnitrophica WOR_2 bacterium RBG_13_41_10.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1801849 {ECO:0000313|EMBL:OGX15695.1, ECO:0000313|Proteomes:UP000179249};
RN [1] {ECO:0000313|EMBL:OGX15695.1, ECO:0000313|Proteomes:UP000179249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the RNase E/G family. RNase G subfamily.
CC {ECO:0000256|ARBA:ARBA00005663}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGX15695.1}.
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DR EMBL; MHGH01000013; OGX15695.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1ME81; -.
DR STRING; 1801849.A2166_02900; -.
DR Proteomes; UP000179249; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.1260.20; Ribonuclease E, catalytic domain; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR048583; RNase_E_G_thioredoxin-like.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF1; RIBONUCLEASE E_G-LIKE PROTEIN, CHLOROPLASTIC; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR Pfam; PF20833; RNase_E_G_Thio; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 39..102
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
SQ SEQUENCE 479 AA; 55441 MW; 96279DFD8FC63A24 CRC64;
MPREILINIE TQEKRVAITS DGRLEEFYIE RPQDKTIVGN IYKGKIEAVL PSLGAAFVDI
GLAKKGFLYL SELESLYEAL EPKEVKSREV KKGQEVMVQV VKESFGTKGP RISCHIGLPG
RYLVLMPQDN QIGISRRIED EEERRRLRQV LSELKLPKNL GFIVRTAASG RSRNELLRDA
RFLLKLWQRT EKISQRKQSP ALIYEEYDLT LRAIRDSFTE DVHKLIIDSK PEFYRVQRFM
KTFLRYLANK VELYRGQDLF EDKDIERQIN KIFENKVYFK SKGYIVIEPT EGLVVIDVNS
GGFRSKAGHE DAAFKVNCEA AEEVARQLRL RDLGGIIVID FIDMEKEGHR REVLNVLKKA
LNEDKAKYDI TGISEFGLVE MTRERVHNTV QTLSYESCPY CQGRGKVKSK TTLAIFVLRQ
LKRFLKTKNM REVTVYLHPS VIEEISKNSQ NLKGLERQFR ARIHLVAEPA CHIEEIKIS
//
