ID   A0A1G1MF65_9BACT        Unreviewed;       732 AA.
AC   A0A1G1MF65;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=CHAT domain-containing protein {ECO:0000259|Pfam:PF12770};
GN   ORFNames=A2166_05260 {ECO:0000313|EMBL:OGX16025.1};
OS   Omnitrophica WOR_2 bacterium RBG_13_41_10.
OC   Bacteria; Candidatus Omnitrophota.
OX   NCBI_TaxID=1801849 {ECO:0000313|EMBL:OGX16025.1, ECO:0000313|Proteomes:UP000179249};
RN   [1] {ECO:0000313|EMBL:OGX16025.1, ECO:0000313|Proteomes:UP000179249}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=27774985; DOI=10.1038/ncomms13219;
RA   Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA   Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA   Williams K.H., Hubbard S.S., Banfield J.F.;
RT   "Thousands of microbial genomes shed light on interconnected biogeochemical
RT   processes in an aquifer system.";
RL   Nat. Commun. 7:13219-13219(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OGX16025.1}.
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DR   EMBL; MHGH01000010; OGX16025.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G1MF65; -.
DR   STRING; 1801849.A2166_05260; -.
DR   Proteomes; UP000179249; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR024983; CHAT_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR10098; RAPSYN-RELATED; 1.
DR   PANTHER; PTHR10098:SF106; TETRATRICOPEPTIDE REPEAT PROTEIN 28; 1.
DR   Pfam; PF12770; CHAT; 1.
DR   Pfam; PF13424; TPR_12; 3.
DR   SMART; SM00028; TPR; 6.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50005; TPR; 3.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        377..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          76..350
FT                   /note="CHAT"
FT                   /evidence="ECO:0000259|Pfam:PF12770"
FT   REPEAT          479..512
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          563..596
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          603..636
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   732 AA;  85054 MW;  6270A073FE83FE53 CRC64;
     MAQNSNGLVL EVLKQDNNLA VSIFEKEEIA STVRHYSQLP FSDVEINKLC REITFILNKA
     NRDGKLDENA LNNLKKTGQL LWDQLLTGQV KDRLRTTEAS HLLLSLDEEL INIPWELLYT
     GEEFLCLKFG LGRVIRTKDK LNQPQYRSQQ SKLKMLILAN PTNDLKSAYL EGLHTKNQFD
     KKRNEISIDF KSTYIDTWYV KKNLRDYDIV HFAGHCAYNP HDPKTSGWVL SDGKFSLVDI
     LALSQGSVLP SLVFSNACHS AQVLDNMLAT DYQDRAYSLA SAFLFAGVRH YIGTIHKIED
     PASLVFATEF YTQLICAKSV GECIRQGRLK LIEQYGVHTV HWANHLLYGD PNFAFFRPKE
     KAGKSQRQAR FVLYKKYTVK LLMALFILSA GIFFYRGWVA VNPGAYFSYL ASERYFLEGK
     NEKVILKLTG LIQRDPLYLP AYALLAQAYQ RLGNKELIFK YYFDYMLYSQ KKGDKFNLAK
     GYVSVGWAYQ NQGDYPKAFD FYDKALTYSR ENNDKLNEAL VLRKMAVWYI DKQDYDKALE
     LLLKSSEINR PREHLSEHRY NLACDYFDIG LVFSDKDDFK TAREFYEKSL RIFEKLKMKN
     ELSDYYFNLG EIYLMEKQYQ KALDSYTKGL KIDQMQHNLP SIAADYNMIG ELYLEMDNLV
     DAEKFFKQAL EACKGIDAPL ELACAYYNLG LLYKEKGQKN RTREYLRQAQ EIYVKIDTPD
     YQEIKQEFLS LD
//