ID A0A1G1N1R0_9BACT Unreviewed; 342 AA.
AC A0A1G1N1R0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN ORFNames=A3J51_06895 {ECO:0000313|EMBL:OGX23639.1};
OS Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_02_FULL_45_21.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1801854 {ECO:0000313|EMBL:OGX23639.1, ECO:0000313|Proteomes:UP000178464};
RN [1] {ECO:0000313|EMBL:OGX23639.1, ECO:0000313|Proteomes:UP000178464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGX23639.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MHGN01000063; OGX23639.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1N1R0; -.
DR STRING; 1801854.A3J51_06895; -.
DR Proteomes; UP000178464; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR017200; PqqE-like.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR PIRSF; PIRSF037420; PQQ_syn_pqqE; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 27..265
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 342 AA; 39441 MW; 35BEB61DBCAE158F CRC64;
MERASFLTQY QGRINRLYKD GLLPKYFKAP VFTLWELTDR CNLSCVHCYY NSNQKSENEL
TTKEALNIIE QLAKMKVFEV YLTGGEALLR EDWPVLIERL RQKKIQVGLI TNGTQIDRNA
AGKLADLKVK WVQISIDGAS PGVHDKVRGL SGSWEKSVAA IRYLKQNNIR THLSFVPTRI
NFRDVKGVIG LCVEMGLEYF VTDMLVLTGR AVKNFEQIKL GPEEYVEFYA LLDEAAKIYT
DKLTIIAPSR EKETLKTYVK TRSAPPNIWC IITPQGACRL DLLLPFTYGD LKSQKLEYIW
NHFLREGWHR PEVIEFINSL NMMSDLIKHK TVPYVSENIH CQ
//
