ID A0A1G1P707_9BACT Unreviewed; 503 AA.
AC A0A1G1P707;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OGX37689.1};
GN ORFNames=A3D87_03985 {ECO:0000313|EMBL:OGX37689.1};
OS Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_02_FULL_50_17.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1801857 {ECO:0000313|EMBL:OGX37689.1, ECO:0000313|Proteomes:UP000177986};
RN [1] {ECO:0000313|EMBL:OGX37689.1, ECO:0000313|Proteomes:UP000177986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGX37689.1}.
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DR EMBL; MHGQ01000049; OGX37689.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1P707; -.
DR STRING; 1801857.A3D87_03985; -.
DR Proteomes; UP000177986; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT DOMAIN 16..157
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 212..449
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 503 AA; 57403 MW; 4379505A283603D9 CRC64;
MSQLDILFIH SDSAKKNYQD LSKDFSAVEP PIWAGMLASH CLHKGFSAEI LDCAALRLSD
QEAAYRIQEL NPRAACFVVY GQQPSASSQN MDGAVALAGT LKEVWPQGKT LFVGGHVAAL
PREVLEKHPC VDMVCQNEGV YTISNLLRTN LEDKLEQVDG LGYRQDGEII LNKPSPIVSR
WDLPQELPGV AWDKLPLERY RTSLWHSYPN NCQRQPFAAL YTSLGCPMRC SFCMINIINR
QENEYADGSA IFRYWDPDFI IEEFDGFAKK GIKNIKIADE LFVLNTNHFM RLCELIIERG
FNFNIWCYSR VDTVKEHFLE TLKRAGVKWL ALGIESGNTK VRQDVTKGRF EDVDIRAVVK
KIRDHDICVI ANYIFGLPED TMATMQMTLD LALELNTEEV NFYSAMAYPG SPLYGEAKKK
GWRLPDCYAG YSQHSYYTQP LPTRYLTADQ VLAFRDKAWM TYHTHPQFLN LLKQKFGQTA
VDETLRSTQI QLKRKILEEA SVL
//
