ID   A0A1G1PU65_9BACT        Unreviewed;       175 AA.
AC   A0A1G1PU65;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=Cation:proton antiporter {ECO:0008006|Google:ProtNLM};
GN   ORFNames=A3G38_03480 {ECO:0000313|EMBL:OGX45478.1};
OS   Omnitrophica WOR_2 bacterium RIFCSPLOWO2_12_FULL_51_8.
OC   Bacteria; Candidatus Omnitrophota.
OX   NCBI_TaxID=1801870 {ECO:0000313|EMBL:OGX45478.1, ECO:0000313|Proteomes:UP000179910};
RN   [1] {ECO:0000313|EMBL:OGX45478.1, ECO:0000313|Proteomes:UP000179910}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=27774985; DOI=10.1038/ncomms13219;
RA   Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA   Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA   Williams K.H., Hubbard S.S., Banfield J.F.;
RT   "Thousands of microbial genomes shed light on interconnected biogeochemical
RT   processes in an aquifer system.";
RL   Nat. Commun. 7:13219-13219(2016).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E
CC       family. {ECO:0000256|ARBA:ARBA00006228}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OGX45478.1}.
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DR   EMBL; MHHD01000028; OGX45478.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G1PU65; -.
DR   Proteomes; UP000179910; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002758; Cation_antiport_E.
DR   PANTHER; PTHR34584; NA(+)/H(+) ANTIPORTER SUBUNIT E1; 1.
DR   PANTHER; PTHR34584:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT E1; 1.
DR   Pfam; PF01899; MNHE; 1.
DR   PIRSF; PIRSF019239; MrpE; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        39..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   175 AA;  19609 MW;  255598B6801423F1 CRC64;
     MREYSAGGSG AVKSKLILFV IGFIVWMLLG WPIDAQHAIV GIFAAGLAAF LTGDLFTRRP
     HHFGHISRYL WFCYYVPLFL WECLKANIDV AARVLNPRLP INPGIVKVMT SLRSDTALTF
     LANSITLTPG TLCVDISPEE GILYIHWIDV KSQDTQEAAQ RIVKTFEGVL KRIFE
//