ID A0A1G1PZE7_9BACT Unreviewed; 560 AA.
AC A0A1G1PZE7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=CBS domain-containing protein {ECO:0000259|PROSITE:PS51371};
GN ORFNames=A2243_03975 {ECO:0000313|EMBL:OGX47272.1};
OS Omnitrophica WOR_2 bacterium RIFOXYA2_FULL_38_17.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1801873 {ECO:0000313|EMBL:OGX47272.1, ECO:0000313|Proteomes:UP000179162};
RN [1] {ECO:0000313|EMBL:OGX47272.1, ECO:0000313|Proteomes:UP000179162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGX47272.1}.
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DR EMBL; MHHG01000064; OGX47272.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1PZE7; -.
DR Proteomes; UP000179162; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR43021; NA(+)/H(+) ANTIPORTER-RELATED; 1.
DR PANTHER; PTHR43021:SF2; NA_H_EXCHANGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 430..489
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 560 AA; 61373 MW; 0B56A8736AECE0AF CRC64;
MEKFLHLFSN ISYFHVNMLF ILGIALFGGT IGGRLFQKMK VPQVVGYIVI GILLGPMGIK
IINTEMVNVL QPLTYFALGL IGFMIGGELK KNVIIRYGKQ FFYILLFEGI FSFILVAISV
GLFGTYFFKN ANLGWGLGLL FGSIASATAP AATTDVLWEY RTRGPLTTTI FGIVALDDAL
AIFLFAISAS FATRIMGTTQ NSLMISILHP LYEIGGAVLV GAISGTILVK ILHKYNEEER
VLAFLIGIVL FVLGISLAIN VSMLLASMVL GAVVVNGAPN ISKNIFKLLA GFTPPIFILF
FVFIGSKLNF SQVNPLVFGL VLVYLVSRTI GKMSGAFLGA YVSQAPKTVR KYLPFCLFSQ
AGVAIGLSIV AAHLLPEDLG NIIIIVITST TFVVQLIGPS CVRYGISKAG EIGLNITEED
IIKKIKIADI IEENAPLIKQ NTSLDEILRN FSKYPYFYYP VVGNDKKLIG IISIDSVRHV
FRDKDVGAFV LAEDILEPVQ IKIGATASGL EAKELFDKYH IDFVPVVDEN DVVVGGLEER
IFYRFITRKQ VEIEQKVLSL
//
