ID A0A1G1TD69_9BACT Unreviewed; 805 AA.
AC A0A1G1TD69;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Mechanosensitive ion channel protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BEN49_10010 {ECO:0000313|EMBL:OGX88818.1};
OS Hymenobacter coccineus.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Hymenobacter.
OX NCBI_TaxID=1908235 {ECO:0000313|EMBL:OGX88818.1, ECO:0000313|Proteomes:UP000177506};
RN [1] {ECO:0000313|EMBL:OGX88818.1, ECO:0000313|Proteomes:UP000177506}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCM 8649 {ECO:0000313|EMBL:OGX88818.1,
RC ECO:0000313|Proteomes:UP000177506};
RA Sedlacek I., Kralova S., Kyrova K., Maslanova I., Stankova E., Vrbovska V.,
RA Nemec M., Bartak M., Svec P., Busse H.-J., Pantucek R.;
RT "Hymenobacter coccineus sp. nov., Hymenobacter lapidarius sp. nov. and
RT Hymenobacter glacialis sp. nov., isolated from Antarctic soil.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGX88818.1}.
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DR EMBL; MDZA01000320; OGX88818.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1TD69; -.
DR Proteomes; UP000177506; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 251..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 467..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..535
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 555..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 605..625
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 631..660
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 647..713
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 731..804
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 805 AA; 88171 MW; B8D6B13921531987 CRC64;
MIGLIGWSGQ LQAAPAKPKA TVQKALSAAP ILPDTLARRI EKAYFVLSRI NGTARRNSDT
QDLSEDLPAV EDNLETIREN LDQYGDVVDV KQLQMYRVLL ADMQTRLGDW RTALNTGGKE
LAAQQARLDT LGAQLPPPAD RPPVATAIGR ALARLAGKED RARQLLARRR QSVTGLQTRV
SEGYIQALEL QDVVREQMGR FNRRNIRAEL PPLWRPGRVV AADAQANALV RKSYQAQRGL
LGYYFTEHWD YWVWMVLLAV GFFGWVFRNF RALRHTAAGA AIAANADAPA ANSPAAAGAD
AAATGAPAAA TAAPRALPEH RLHYLRPIPV AAALLVVFSL APFFDLQPPA AYTDLLQLLL
VVTLTVLGWR SWPRPLFWYW AGIVVAFFAL NVAYAVRAPG LGMRWATLLL NVAAGALGYF
FWRYLQRRKL LAGFVRPVAL LFVGLNALAV LANAFGRVSL AKMFTAAALV GLTQGVALSA
FVRVVTEAFF LQVQRSRQAG GLGTRFSFGK MESALRKALT AVVGLLWLML FTANLNLYNL
FYRLIGRALT APHQLGSTTF TLGNVLLFFG VIILTVQLQK YVGYFFGETD DEFNVDTDRK
GSWMVAIRLA ILAVGLFVAT LASGLPVDKI AIVLGALGVG IGLGLQNIIN NLVSGVILIF
ERPFQVGDYI EVKGQTGRVK DIGIRASKLI SQAGSEIILP NGDLLSNHVI NWTLSNNHIR
TEMALNLGPD IDLDQARQII SEEILQNPNT LHKVAPEILL SNVTVTGYDL KALFWINNIR
QEQALKSELL SGIYQRLTQA GIAMR
//
