ID A0A1G1TEE6_9BACT Unreviewed; 954 AA.
AC A0A1G1TEE6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=BEN47_07525 {ECO:0000313|EMBL:OGX89241.1};
OS Hymenobacter lapidarius.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Hymenobacter.
OX NCBI_TaxID=1908237 {ECO:0000313|EMBL:OGX89241.1, ECO:0000313|Proteomes:UP000176294};
RN [1] {ECO:0000313|EMBL:OGX89241.1, ECO:0000313|Proteomes:UP000176294}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCM 8643 {ECO:0000313|EMBL:OGX89241.1,
RC ECO:0000313|Proteomes:UP000176294};
RA Sedlacek I., Kralova S., Kyrova K., Maslanova I., Stankova E., Vrbovska V.,
RA Nemec M., Bartak M., Svec P., Busse H.-J., Pantucek R.;
RT "Hymenobacter coccineus sp. nov., Hymenobacter lapidarius sp. nov. and
RT Hymenobacter glacialis sp. nov., isolated from Antarctic soil.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGX89241.1}.
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DR EMBL; MDZB01000033; OGX89241.1; -; Genomic_DNA.
DR RefSeq; WP_070724398.1; NZ_MDZB01000033.1.
DR AlphaFoldDB; A0A1G1TEE6; -.
DR STRING; 1908237.BEN47_07525; -.
DR OrthoDB; 32195at2; -.
DR Proteomes; UP000176294; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR046818; MmeI_C.
DR InterPro; IPR046819; MmeI_hel.
DR InterPro; IPR046816; MmeI_Mtase.
DR InterPro; IPR046817; MmeI_N.
DR InterPro; IPR046820; MmeI_TRD.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR33841:SF6; DNA METHYLTRANSFERASE A; 1.
DR PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR Pfam; PF20467; MmeI_C; 1.
DR Pfam; PF20465; MmeI_hel; 1.
DR Pfam; PF20473; MmeI_Mtase; 1.
DR Pfam; PF20464; MmeI_N; 1.
DR Pfam; PF20466; MmeI_TRD; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 14..197
FT /note="MmeI-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF20464"
FT DOMAIN 204..281
FT /note="MmeI-like helicase spacer"
FT /evidence="ECO:0000259|Pfam:PF20465"
FT DOMAIN 367..626
FT /note="MmeI-like DNA-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF20473"
FT DOMAIN 650..852
FT /note="MmeI-like target recognition"
FT /evidence="ECO:0000259|Pfam:PF20466"
FT DOMAIN 856..933
FT /note="MmeI-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20467"
SQ SEQUENCE 954 AA; 106932 MW; DAF10DAD088C6D9F CRC64;
MPAAPLAWPE IRQRALAFAR DWKDETREHA EAQTFWNEFF HVFGLTRRKV AEFERNVSKH
APTLAAGLVQ EPAPALGRGR IDLFWPGVLL GESKSRHRDL NDAYRQALEY IGGLPDHEKP
QYVFVSDFAR LRLYDLRGAT VYPAPADHLE IQVADLGKHV RLFGFMAGYQ QRSYQEQDPV
NRAAAERMGR LHDQLAASGY HGTDLERYLV RLLFCLFAED TDIFPRASFM DLVSQHAGPR
GQQLGPLLHQ LFEVLDTPED QRPPALPAHL REFPYVNGDL FKGPLHTVAF SETMRELLLD
ATRLDWGQIS PAIFGSLFQS VMDPAARRTQ GAHYTSEQNI LKALGPLLLD ELRAELAHLK
TLAAGTARDN RLSKLQNRLS ELRLLDPACG CGNFLVVAYR ELRLLEMEIL EVFYPADEVI
QFPLGPETEV RLNADQMHGI EVDEFPARIA EVALWLVDHQ MNQRFSTRFG QYLARIPLRR
GAHIVHANAL QTDWNTVLPR EQATHVVGNP PFVGKQYQSA VQKADVARIF QGVKGASALD
YVACWFLKTA EYLHGTTARA ALVSTNSITQ GEQVSILWGP ILNRFGMKLQ FAHQTFQWRN
EGKRNAAVHC IIVGFGPQEI ANKRLFLYDN PGAAPHEQAA AQLNPYLVDA PTVLLPSRSR
PISDVPALAF GSMPNDGGHL LLNDTKRAEL LAAEPALAPY VRPFKGAEEY INGKSRWCLW
LPNVEPQIIR NSPILQEKAR AIRDYRAASP RDATQRLAGT PLLFGENRQP TTNYLAVPAF
STINRHYVPI GFLTPDIIAS NKVYTCSSVS SYHFGVLTSA MHMAWLRYVG GRLKSDYGYS
KDIVYNNFPW PTQPSEEARQ AVEAAAQAVL DARAAHPGST LADLYDPLAM PPDLRAAHRA
LDARVERLYR AKRFTHDTER VQHLFERYAA LSAPLAPAAA VPAKQRGNQS VKQA
//
