ID A0A1G1TFQ2_9BACT Unreviewed; 985 AA.
AC A0A1G1TFQ2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=BEN49_08465 {ECO:0000313|EMBL:OGX89712.1};
OS Hymenobacter coccineus.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Hymenobacter.
OX NCBI_TaxID=1908235 {ECO:0000313|EMBL:OGX89712.1, ECO:0000313|Proteomes:UP000177506};
RN [1] {ECO:0000313|EMBL:OGX89712.1, ECO:0000313|Proteomes:UP000177506}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCM 8649 {ECO:0000313|EMBL:OGX89712.1,
RC ECO:0000313|Proteomes:UP000177506};
RA Sedlacek I., Kralova S., Kyrova K., Maslanova I., Stankova E., Vrbovska V.,
RA Nemec M., Bartak M., Svec P., Busse H.-J., Pantucek R.;
RT "Hymenobacter coccineus sp. nov., Hymenobacter lapidarius sp. nov. and
RT Hymenobacter glacialis sp. nov., isolated from Antarctic soil.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGX89712.1}.
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DR EMBL; MDZA01000255; OGX89712.1; -; Genomic_DNA.
DR RefSeq; WP_070744543.1; NZ_MDZA01000255.1.
DR AlphaFoldDB; A0A1G1TFQ2; -.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000177506; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF64; ATP-DEPENDENT DNA HELICASE REP; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 2.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 1..495
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 543..795
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT REGION 941..985
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 10..17
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 985 AA; 108087 MW; 2EED7609377B92F8 CRC64;
MSPSFRIYSS SAGSGKTYQL TKEYLTLALS SEDPAYFKRV LAITFTRDAA GEMKERIVGA
LRRFAYPEAG SKPDALLTDV AAALGLGPDA VRRRAAATFR LVLYHYADFA VSTIDAFVQR
IVTAFTRELD LPASFEVELD TDSVLQSAVA ALLDKVNRNA DTRLLSATLA DYALGRADEG
KSWSRLPEEL ATFGRALFNE TVQEAVTELG KLDLADFRRI DKELRARRLE IEAAFTQAQE
AAVAVLDEAG ALEGDFYQGK RGIFGYVQKG TELLAPGAGP NSYVQATLAD DKWYSGKIKT
PADRARVDAV KEPLRQLVTT LDTLRANYLP NYVLLTAMQP YLFHASLLSE LNKLVEQISR
ERNVVLISEF NRRIAAIVLT EPVPFLYERL GEKYEHLLID EFQDTSVLQW NNLLPLVENT
LANGFDSLAV GDAKQSIYRW RGGEMEQILR LHQGNTGPLA DRAREPEMRE LLRLRYETVE
PALKAEALQI NYRSAREIIE FNNSFFAAVS ARHADLPLVQ GIYDAHFGQQ VPAGAPSGQP
GHVELLFTQK DAPAQQYDAA AGAHTGAPLP GHAPGATLTY EESTCYLALA LVEQALANGY
ALADVAVLCR TRQASKIMAK FLKERGYAII SADSLALEFA EVVNLLISIF RVLHQPADTL
ARAEALLLID KVVRLEPPTP ARVRHLADIA NAKLATPFFD ELRALGYDVQ EEETGNLGLY
ELAERLIDLF GLLGRNGESD YLFRFLDLTL EFSLRHGNNL GNFLADWESR KGRVSINAPG
GRAAITITTV HKAKGLAYGV VIVPFADWSL EPHRNTLLWG HLAADEKPLP GLPEVAVVGL
NATLQQTALG PQYDEEREKT FLEGLNTLYV AFTRPRHRLY VLSKRPEARK AAKATPETEE
LGAPLAAART VADLLHGYVL GRGQWQDEQV AFVLSQGAEA PARAGAPRQP AAPTPSPTWG
PHPGRSACNC AATPPRCSIS TSSGT
//
