ID A0A1G1VKM4_9BACT Unreviewed; 375 AA.
AC A0A1G1VKM4;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Glycosyltransferase 2-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2784_00960 {ECO:0000313|EMBL:OGY15931.1};
OS Candidatus Chisholmbacteria bacterium RIFCSPHIGHO2_01_FULL_48_12.
OC Bacteria; Candidatus Chisholmbacteria.
OX NCBI_TaxID=1797589 {ECO:0000313|EMBL:OGY15931.1, ECO:0000313|Proteomes:UP000177324};
RN [1] {ECO:0000313|EMBL:OGY15931.1, ECO:0000313|Proteomes:UP000177324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006739}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGY15931.1}.
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DR EMBL; MHCH01000055; OGY15931.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1VKM4; -.
DR STRING; 1797589.A2784_00960; -.
DR Proteomes; UP000177324; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004582; F:dolichyl-phosphate beta-D-mannosyltransferase activity; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd06442; DPM1_like; 1.
DR InterPro; IPR039528; DPM1-like.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR007267; GtrA_DPMS_TM.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43398:SF2; DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43398; DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR Pfam; PF04138; GtrA; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 245..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..143
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
FT DOMAIN 247..373
FT /note="GtrA/DPMS transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04138"
SQ SEQUENCE 375 AA; 43221 MW; 8CC8A5B1956C3FBC CRC64;
MKRAVVILPT YNERENIAPL IRQLQDQFRH ITNYRMSILV VDDNSPDGTQ TVVRELLLKH
PNVHLLTGPK QGLGKAYLRG MDYAINDLNA DVVLEMDADW QHNPKQIPEF LDKLDQGYDI
IVGARYIPGG SVPKNWGWHR KIFSRVGNLL VRLSLMRFNQ HEWTNGFRAI RSSVYLRVRD
KLLDYTGYTF QVAFLHQALL LNKKIGEIPN KFADRRWGKS KIGAEYIKNL LLYLVQQTLI
NPPQFLRFLV VGGIGFIVQF ITFRLLRGAD LRPALATALS AEVAIVSNFI WNNSWTFADQ
KIFTVKQILI KFFQFNLTSL GSIIIQAIIS EIGTRTLGIR YLAFGINTDD VYLMIGILVG
LFWNYTMYKL VIWKK
//
