ID A0A1G1WNS9_9BACT Unreviewed; 292 AA.
AC A0A1G1WNS9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 13-SEP-2023, entry version 12.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|RuleBase:RU361259};
GN ORFNames=A3F35_00295 {ECO:0000313|EMBL:OGY29359.1};
OS Candidatus Woykebacteria bacterium RIFCSPHIGHO2_12_FULL_45_10.
OC Bacteria; Candidatus Woykebacteria.
OX NCBI_TaxID=1802603 {ECO:0000313|EMBL:OGY29359.1, ECO:0000313|Proteomes:UP000178068};
RN [1] {ECO:0000313|EMBL:OGY29359.1, ECO:0000313|Proteomes:UP000178068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872,
CC ECO:0000256|RuleBase:RU361259};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890, ECO:0000256|RuleBase:RU361259}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGY29359.1}.
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DR EMBL; MHCZ01000035; OGY29359.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G1WNS9; -.
DR STRING; 1802603.A3F35_00295; -.
DR Proteomes; UP000178068; Unassembled WGS sequence.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR CDD; cd02541; UGPase_prokaryotic; 1.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR01099; galU; 1.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU361259,
KW ECO:0000313|EMBL:OGY29359.1};
KW Transferase {ECO:0000256|RuleBase:RU361259, ECO:0000313|EMBL:OGY29359.1}.
FT DOMAIN 7..267
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 292 AA; 32782 MW; 91669E72599DD096 CRC64;
MKKITKCIIP AAGYGTRFLP ATKAMPKEML PIVDKPIIQY VVEEAVSSGI EDIILVTGGN
KRAIEDHFDR SQELESWLKE AGKEEQLEEI IKIAHLANFI YVRQKGPYGN ATPVLSAKHL
VEDEPFAVLW GDEFIYSQPP RLKQLIDCFE KYGKTVISGV RIDDEEELSK YGISKIEPLE
ENVYRILDIV EKPTAAEAPS NLATHGAYIF TPTIFPCLEN LKPGKGGELW LPEAVKELLK
TEPVYAVEIK NGKYYDTGDK LGYLKAIIDI SLKHPDFGEA VKSYLKKTLA RL
//
