ID A0A1G2CMT9_9BACT Unreviewed; 510 AA.
AC A0A1G2CMT9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Tr-type G domain-containing protein {ECO:0000259|PROSITE:PS51722};
GN ORFNames=A2946_04050 {ECO:0000313|EMBL:OGZ02724.1};
OS Candidatus Liptonbacteria bacterium RIFCSPLOWO2_01_FULL_53_13.
OC Bacteria; Candidatus Liptonbacteria.
OX NCBI_TaxID=1798651 {ECO:0000313|EMBL:OGZ02724.1, ECO:0000313|Proteomes:UP000178348};
RN [1] {ECO:0000313|EMBL:OGZ02724.1, ECO:0000313|Proteomes:UP000178348}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007733}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGZ02724.1}.
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DR EMBL; MHLB01000002; OGZ02724.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2CMT9; -.
DR Proteomes; UP000178348; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01887; IF2_eIF5B; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43381:SF5; TR-TYPE G DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF11987; IF-2; 1.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 1..194
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 54..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 510 AA; 54478 MW; FE07B6F7EA84EFC6 CRC64;
MGHVDHGKTT LLDYIRKTSV AAREAGGITQ SIGAYEIIHK AQISADEGLI SADERGPISA
NPRVDPHKSA SPEGRRITFI DTPGHEAFSK MRARGAHVAD LAILVVAADD GVKPQTTESI
KILHESKTPF VVAITKIDKN GADVERVKND LANAGVLLEG YGGQVSYQPV SSKSGDHVDE
LLDLLLLAAD VENLTYDPEA PASGFVLETK MDRRRGLEAT VIVKNGTLRH GTPIATKTAQ
GNIRILENFI GEVRKELSPS APALVIGFES LPQVGEEFSS GTMPELLDAA IKGNSTRTTT
AANVAPDERP NCLRIIVKAS DTGSLEALYG IIHAMAESKP IQIVGDAVGE VNDNDIRLAM
STKAMVIAFK CKADKTAKML ADVNGIRIIS SEIIYDLTRA IEEYLTEQAK PKSEGELEVL
AVFNAEKQEK QVVGGRVTHG VVRNKTQFTL MRGSTSLTTG EGVPAGKGRI GNLQQEKKDA
HEVREGNECG LLVSADTMVK IGDKIVVAGA
//
