ID A0A1G2EZB3_9BACT Unreviewed; 685 AA.
AC A0A1G2EZB3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=A2931_01065 {ECO:0000313|EMBL:OGZ31139.1};
OS Candidatus Niyogibacteria bacterium RIFCSPLOWO2_01_FULL_45_48.
OC Bacteria; Candidatus Niyogibacteria.
OX NCBI_TaxID=1801724 {ECO:0000313|EMBL:OGZ31139.1, ECO:0000313|Proteomes:UP000177486};
RN [1] {ECO:0000313|EMBL:OGZ31139.1, ECO:0000313|Proteomes:UP000177486}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGZ31139.1}.
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DR EMBL; MHMQ01000005; OGZ31139.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2EZB3; -.
DR Proteomes; UP000177486; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 314..359
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 451..672
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 685 AA; 75400 MW; 7F1AB5EE28C0CB8D CRC64;
MNKIRFFPAL IIVLAVAMLA ANGLWLLPAI DALNAGVSNL HLEVARRASS ALRDSINVNR
KALKESASLI GQDPRSAGEI MARLLNNNPS IEEAVFVDMN GAEKARVSRT KFISSKELVS
RKGEASFEEI ASGRKIEYGG PVFFSLLAEP LVDFSVQIKN PSGSPVGVLV AENNLRFVWD
LMSQVNVGGA GTAYVVDQNK NLIAHPNPSI VLRGENLSYR PIVNQVVSGR VVDGLSADDP
YINFEGEKVF AVGLPVENLG WGVIVENNYD EAFSSRRRVI VFALFFIVSV IGLFAVIFWS
LRRIIGLFAA LELEKKQTSA IISNLTDGLI EYTDDFKIIL VNPSAENILG IRADEIIGRR
FEPKDSTNLK FSSFSKVLFP ILAEDARAIR ADGDHLKMIE LKIHHPLDRD LQIITVPVLG
EQGRIFSYLK VIRDISREKA IAKTKSEFIS LAAHQLRTPL SAIKWVFSMI LSGDMGPVGP
EIKPLIDTGF RSNERMIALV NDLLNVARIE EGRFGYKFEP GNLVETVKDV VDSFDILSKE
YGTKIKFIPP GSSFPAMVYD KEKLSLAINN LIDNAMRYTH KSDGLIEVGV FADGDFAKIS
VKDNGIGISK EQLERLFTKF HRGPNAIKMY TEGSGLGLFI VKNIVKRHGG DVVVESEEGQ
GSVFTLLLPI DASKIPPVAE VYEGV
//
