ID A0A1G2F456_9BACT Unreviewed; 571 AA.
AC A0A1G2F456;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Penicillin-binding protein transpeptidase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2V69_03205 {ECO:0000313|EMBL:OGZ32809.1};
OS Candidatus Portnoybacteria bacterium RBG_13_40_8.
OC Bacteria; Candidatus Portnoybacteria.
OX NCBI_TaxID=1801990 {ECO:0000313|EMBL:OGZ32809.1, ECO:0000313|Proteomes:UP000177810};
RN [1] {ECO:0000313|EMBL:OGZ32809.1, ECO:0000313|Proteomes:UP000177810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGZ32809.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MHMT01000013; OGZ32809.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2F456; -.
DR STRING; 1801990.A2V69_03205; -.
DR Proteomes; UP000177810; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 1.10.150.770; -; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 73..208
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 251..554
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 571 AA; 64334 MW; 36B7823A324A92EE CRC64;
MKNWRFYTFV FFIGLIFIVV VLRLFSLQII KHSFYKKLAA NQHQNFETVY PVRGEIFMKD
KHTNSDSRSL LFPIAINKDY WTIYAVPKEI KEKEETVTKL SPLLNINEEE LKKKISKLND
PYELLKNKVE EENYNKIKDL SIDGVYFQKE SWRYFPAGEM ACHLVGFVGF YGDEKIGRYG
LEEHYEEKLS GKTGFIEAKR DSLGELINVG EKILAVPEDG ADLILTIDPN IQYFIEGKIK
QRVQELEATS GTIIVMEVKS GAIKAMASWP TFNPNKYNEV EDIGLFLNPV IDGVFEPGSV
FKIITMAAAL DKGLIDPNTT YEDKGFVEIS GHIIKNATEK ANGVQTMTQV LEKSLNSGAI
FVQQKLGKDN FKDYVEKFGF GQKTGIDLSG EEKGNISNLK KKKDLEYATA SFGQGIAVTP
IQLVVAFGAI ANDGVLLRPY IVEKVIYKSG EEKIIQSQEI RRVISSDAAS RLTAMMVSTV
KNSFDKKAWV PGYSVAGKTG TAQIPDLEKG GYSDETIHTF GEFFPAYDPR FVLLIKVDKP
KGIRFAADSI TPLGRQITEY ILNYYEIPPS Q
//
