ID A0A1G2H520_9BACT Unreviewed; 439 AA.
AC A0A1G2H520;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Serine--tRNA ligase {ECO:0000256|ARBA:ARBA00039158};
DE EC=6.1.1.11 {ECO:0000256|ARBA:ARBA00012840};
DE AltName: Full=Seryl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031113};
DE AltName: Full=Seryl-tRNA(Ser/Sec) synthetase {ECO:0000256|ARBA:ARBA00033352};
GN ORFNames=A2827_00960 {ECO:0000313|EMBL:OGZ57420.1};
OS Candidatus Spechtbacteria bacterium RIFCSPHIGHO2_01_FULL_43_30.
OC Bacteria; Candidatus Spechtbacteria.
OX NCBI_TaxID=1802158 {ECO:0000313|EMBL:OGZ57420.1, ECO:0000313|Proteomes:UP000177932};
RN [1] {ECO:0000313|EMBL:OGZ57420.1, ECO:0000313|Proteomes:UP000177932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- PATHWAY: Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec)
CC biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.
CC {ECO:0000256|ARBA:ARBA00005045}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGZ57420.1}.
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DR EMBL; MHOD01000031; OGZ57420.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2H520; -.
DR STRING; 1802158.A2827_00960; -.
DR Proteomes; UP000177932; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004828; F:serine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 1.10.287.40; Serine-tRNA synthetase, tRNA binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002317; Ser-tRNA-ligase_type_1.
DR InterPro; IPR015866; Ser-tRNA-synth_1_N.
DR InterPro; IPR042103; SerRS_1_N_sf.
DR InterPro; IPR010978; tRNA-bd_arm.
DR NCBIfam; TIGR00414; serS; 1.
DR PANTHER; PTHR43697:SF1; SERINE--TRNA LIGASE; 1.
DR PANTHER; PTHR43697; SERYL-TRNA SYNTHETASE; 1.
DR Pfam; PF02403; Seryl_tRNA_N; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PIRSF; PIRSF001529; Ser-tRNA-synth_IIa; 1.
DR PRINTS; PR00981; TRNASYNTHSER.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF46589; tRNA-binding arm; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OGZ57420.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 200..423
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT COILED 30..101
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 439 AA; 50210 MW; FD5CE7A8F96DE4D4 CRC64;
MIDLKLLREK PEIFKKAARN KNFEIDIDKI LDLDRKRRDA ARAVDNLRAE QNSASEIIAG
EKDKDEKKDI IGKMRNLKAD LEKSEESLKN IDAELSSLLM QIPNVPFDNV PVGKNDKDNV
VLREVGKKQI FAFEPKDYMK IAKQRGWIDV ERASKVSGSR FGYIKGELAL LEFAIIRYVF
DFLMNSERLN KVIQSAACDV RDTAFMPVLP PVVVKPEYMD AMGFLTGDIA EDMYFLEKDN
LYLVGTSEQS IGPMHSGETF NDSNLPLRYV GFSTCFRREA GSYGKDTKGI LRVHQFDKIE
MISFCHPEKS RDEHRFLLAL NEAMMNEFEL PYRVVHISTG DMGLSKAEQF DIETWIPSEN
TYRETHSASN ITDFQARRLN IKHKGNDKSG YVHMLNATAF AIGRILIAII ENFQTEDAKV
KIPKELQSYL GRVEIPSQK
//
