ID   A0A1G2HLS7_9BACT        Unreviewed;       579 AA.
AC   A0A1G2HLS7;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=TGS domain-containing protein {ECO:0000259|PROSITE:PS51880};
GN   ORFNames=A2639_03170 {ECO:0000313|EMBL:OGZ63171.1};
OS   Candidatus Staskawiczbacteria bacterium RIFCSPHIGHO2_01_FULL_34_27.
OC   Bacteria; Candidatus Staskawiczbacteria.
OX   NCBI_TaxID=1802199 {ECO:0000313|EMBL:OGZ63171.1, ECO:0000313|Proteomes:UP000178991};
RN   [1] {ECO:0000313|EMBL:OGZ63171.1, ECO:0000313|Proteomes:UP000178991}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=27774985; DOI=10.1038/ncomms13219;
RA   Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA   Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA   Williams K.H., Hubbard S.S., Banfield J.F.;
RT   "Thousands of microbial genomes shed light on interconnected biogeochemical
RT   processes in an aquifer system.";
RL   Nat. Commun. 7:13219-13219(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OGZ63171.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MHOL01000005; OGZ63171.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G2HLS7; -.
DR   Proteomes; UP000178991; Unassembled WGS sequence.
DR   GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR   CDD; cd05399; NT_Rel-Spo_like; 1.
DR   CDD; cd01668; TGS_RSH; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR007685; RelA_SpoT.
DR   InterPro; IPR004095; TGS.
DR   InterPro; IPR012676; TGS-like.
DR   InterPro; IPR033655; TGS_RelA/SpoT.
DR   PANTHER; PTHR21262:SF31; BIFUNCTIONAL (P)PPGPP SYNTHASE_HYDROLASE SPOT; 1.
DR   PANTHER; PTHR21262; GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE; 1.
DR   Pfam; PF13328; HD_4; 1.
DR   Pfam; PF04607; RelA_SpoT; 1.
DR   Pfam; PF02824; TGS; 1.
DR   SMART; SM00954; RelA_SpoT; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR   SUPFAM; SSF81271; TGS-like; 1.
DR   PROSITE; PS51880; TGS; 1.
PE   4: Predicted;
FT   DOMAIN          390..451
FT                   /note="TGS"
FT                   /evidence="ECO:0000259|PROSITE:PS51880"
SQ   SEQUENCE   579 AA;  67367 MW;  6F89A3C0B69DD69F CRC64;
     MQNQAQQLIK KSTDPKLIGD VFEFAKQIYT DKKWLQGKDL YIDHVLRMAI NLQDMEIDKI
     TIATSLLYGV ADTSLPGEKK HIINEVEKKF GKEIAGLVKK TSELNKIYYS FRINNKDHLN
     EAKNENLRKM FFAIAKDVRV IIIKIASRID SLNRLDYLSQ ETKKLYAIET LEIFVPIANR
     LGLGEVKRKL EDLSFAYLYP EKFSWLQENI KEKYEERQKY LKKFIPHLKK ILKHERIKFI
     DINYRAKSYW STYQKLQRHD MNFEKIYDLV ALRLVVSDVA TCYKTLGVIH KYFQPMSGQI
     QDYIAKPKDN GYKSLHTTVF LQKTLPMQKI EKISEIQIKT AEMHKEAQFG ICAHWAYKEK
     IDLLKDQEKL KFSEKIPEFI KTFNIDFFEN QIFVFTPKGD VITLPKESTP IDFAYAVHSD
     VGDHCESAKI DGKIIPLSHK LNSGDVIEII TSLKKKPSQD WLKFVKTGFA RSHIKKIITA
     TFNPIFSVPA FIKKKIFKTG KEKKEEKHQV KKIKASEIYI GGQKGIAVNF AKCCLPKSKD
     ATMAYLAKHR VAVLHKTSCK NFQKIAQKFP ERIIDASWK
//