ID A0A1G2IUP2_9BACT Unreviewed; 428 AA.
AC A0A1G2IUP2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Serine--tRNA ligase {ECO:0000256|ARBA:ARBA00039158};
DE EC=6.1.1.11 {ECO:0000256|ARBA:ARBA00012840};
DE AltName: Full=Seryl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031113};
DE AltName: Full=Seryl-tRNA(Ser/Sec) synthetase {ECO:0000256|ARBA:ARBA00033352};
GN ORFNames=A2358_03100 {ECO:0000313|EMBL:OGZ78515.1};
OS Candidatus Staskawiczbacteria bacterium RIFOXYB1_FULL_37_44.
OC Bacteria; Candidatus Staskawiczbacteria.
OX NCBI_TaxID=1802223 {ECO:0000313|EMBL:OGZ78515.1, ECO:0000313|Proteomes:UP000178650};
RN [1] {ECO:0000313|EMBL:OGZ78515.1, ECO:0000313|Proteomes:UP000178650}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- PATHWAY: Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec)
CC biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.
CC {ECO:0000256|ARBA:ARBA00005045}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGZ78515.1}.
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DR EMBL; MHPJ01000019; OGZ78515.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2IUP2; -.
DR STRING; 1802223.A2358_03100; -.
DR Proteomes; UP000178650; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004828; F:serine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 1.10.287.40; Serine-tRNA synthetase, tRNA binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002317; Ser-tRNA-ligase_type_1.
DR InterPro; IPR015866; Ser-tRNA-synth_1_N.
DR InterPro; IPR042103; SerRS_1_N_sf.
DR InterPro; IPR010978; tRNA-bd_arm.
DR NCBIfam; TIGR00414; serS; 1.
DR PANTHER; PTHR43697:SF1; SERINE--TRNA LIGASE; 1.
DR PANTHER; PTHR43697; SERYL-TRNA SYNTHETASE; 1.
DR Pfam; PF02403; Seryl_tRNA_N; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PIRSF; PIRSF001529; Ser-tRNA-synth_IIa; 1.
DR PRINTS; PR00981; TRNASYNTHSER.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF46589; tRNA-binding arm; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OGZ78515.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 180..415
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 428 AA; 48944 MW; 08CE320FF2C0746C CRC64;
MLDLNFIREN SEVVKNACKN KNVQVSVDLV LDLDKEKREL MTEIETLKAE QNKISRGGAE
NQAIFAQAKE IKNKIKEIEP ELEKMDGELK TLLLQLPNIP FEDVPVGSSE DENKVIMTVG
KKPNFSFSPK NHWQIAEPLD LIDKDRATKV AGARFAYLKG PLVILELAMF RFAFDVLTNE
KILSEIAKKA KLKVSTKPFV PVLPPFMIKT EPYSAMDRLE PREERYKIEG EDLWLEGSAE
HVLGTMHMNE TLPENIFPIR YAGYATSFRK EAGTYGKDME GILRMHQFNK LEMECLTTAE
NSLSEHYFLI AIQEYLMQQL GLPYEVVLKC TADIGKPNAR GVDINVWLPG QNKYRETHTA
DYMTDYQARR LQTRVRRKSG KVELVHTNDA TALAERPLIA ILENYQQKDG SVKVPKVLQK
YCGFKIIK
//
