ID A0A1G2PMU2_9BACT Unreviewed; 508 AA.
AC A0A1G2PMU2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 13-SEP-2023, entry version 19.
DE RecName: Full=Ribonuclease Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE Short=RNase Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00335};
GN Name=rny {ECO:0000256|HAMAP-Rule:MF_00335};
GN ORFNames=A2806_04645 {ECO:0000313|EMBL:OHA48951.1};
OS Candidatus Terrybacteria bacterium RIFCSPHIGHO2_01_FULL_48_17.
OC Bacteria; Candidatus Terrybacteria.
OX NCBI_TaxID=1802362 {ECO:0000313|EMBL:OHA48951.1, ECO:0000313|Proteomes:UP000177629};
RN [1] {ECO:0000313|EMBL:OHA48951.1, ECO:0000313|Proteomes:UP000177629}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000256|HAMAP-
CC Rule:MF_00335}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHA48951.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MHSS01000002; OHA48951.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2PMU2; -.
DR STRING; 1802362.A2806_04645; -.
DR Proteomes; UP000177629; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00077; HDc; 1.
DR CDD; cd22431; KH-I_RNaseY; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR HAMAP; MF_00335; RNase_Y; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR017705; Ribonuclease_Y.
DR InterPro; IPR022711; RNase_Y_N.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR03319; RNase_Y; 1.
DR PANTHER; PTHR12826; RIBONUCLEASE Y; 1.
DR PANTHER; PTHR12826:SF15; RIBONUCLEASE Y; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF12072; RNase_Y_N; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00335};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00335};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00335}.
FT DOMAIN 324..417
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT COILED 54..120
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 149..176
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 508 AA; 56878 MW; 5AA2986A69939E9F CRC64;
MTFGIVIAAA LALAAGLGIG WYLWSSLPAK QKEKAEASAK SIRERAEADA KSFILSAKDE
AHKLLEEAKQ EERERLRALE RRESEFVVRE RELLSDRKRI DQERDALQRK QGELDNRAKE
IEILHAQELK KLEEVAHLSV EEAHSKLLEQ IEKQHAEEFE RKLQQFERQA QQDLQERARD
ILITAIQRYG ASHASEVTTT SVALPSEELK GRIIGKEGRN IKAFERASGC ELLVDDTPGA
VVISGFDPVR REVAKRALEK LLVDGRMQPA RIEEVVAGCQ GEVDEIIRKA GEDAIQEVGV
VGLDPRLVYL LGRLRFRTSF GQHVLQHSIE AAHLAGMIAA EIGANVQVAK KGALFHDIGK
AIDHEVEGTH VEIGRKLLAR FGVEEPVIKA MQSHHEEYPF ETPESVIVKV AESISAARPG
ARRDTVENYL RRLSDLERIA TSFPGVEKAY AIQAGREVRV FVVPEEVDDL AAKKLARAVA
DQIEQELQYP GEIKVNVVRE TRVAEFAR
//
