ID A0A1G2PYT1_9BACT Unreviewed; 557 AA.
AC A0A1G2PYT1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Penicillin-binding protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2Z62_02215 {ECO:0000313|EMBL:OHA53494.1};
OS Candidatus Terrybacteria bacterium RIFCSPLOWO2_02_42_20.
OC Bacteria; Candidatus Terrybacteria.
OX NCBI_TaxID=1802370 {ECO:0000313|EMBL:OHA53494.1, ECO:0000313|Proteomes:UP000177649};
RN [1] {ECO:0000313|EMBL:OHA53494.1, ECO:0000313|Proteomes:UP000177649}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHA53494.1}.
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DR EMBL; MHTA01000033; OHA53494.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2PYT1; -.
DR STRING; 1802370.A2Z62_02215; -.
DR Proteomes; UP000177649; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 44..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 108..178
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 218..538
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 557 AA; 61643 MW; F0E4C2686CC8C21B CRC64;
MFGRKKYDHK IYPDEIFLDS KNISGFDTSQ FEGRLEKPIG KKTFIYMGTL IGFLGLFLVL
RIFLLQIFEG EKFTARSERN SFKKENIIPL RGAIYDSSGT PLVWNGEEGR TYADIPGLGH
ILGYTGLPSK EDFKKNPDLL SENIVGKDGL EEKYDEVLKG IAGVKLTEKD SQSNPVSESV
QILPQNGRNL TLTIDSKVQS YLYTTMESVA KERNFEGGAA VVMDVSDGNI LAMASVPEYS
SKVLSEGGPA SLISGYINDK NKPFLNRAIS GLYAPGSIVK PFVALAALNE RIISPGKKIL
STGSISIKNP FFPDKKSIFK DWKAHGWVDM RHALAVSSDV YFYEIGGGYQ DIRGLGINKI
YEYAKKFGLG EKTGIDLNGE AEGTVPNPQV KEKNNLDDPL WRVGDTYISA IGQGYFLTTP
IEMAVYASSI ANNGKVVVPR LIKNENFYSE VPQKNAGISE EYFKIVKEGM RMAVTEGTAQ
GLSYPDLKIA AKTGTAEVGG KKNFSHSWVI GFYPYENPKY AFVAVLEKGP AGNTIGAPYA
MKQFFDWLKL YHPEYTR
//
