ID A0A1G2R152_9BACT Unreviewed; 567 AA.
AC A0A1G2R152;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Penicillin-binding protein transpeptidase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A3C04_01210 {ECO:0000313|EMBL:OHA66427.1};
OS Candidatus Wildermuthbacteria bacterium RIFCSPHIGHO2_02_FULL_45_25.
OC Bacteria; Candidatus Wildermuthbacteria.
OX NCBI_TaxID=1802450 {ECO:0000313|EMBL:OHA66427.1, ECO:0000313|Proteomes:UP000178092};
RN [1] {ECO:0000313|EMBL:OHA66427.1, ECO:0000313|Proteomes:UP000178092}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHA66427.1}.
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DR EMBL; MHTV01000033; OHA66427.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2R152; -.
DR Proteomes; UP000178092; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 56..207
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 248..550
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 567 AA; 62634 MW; 3CEEDA1DED22045E CRC64;
MARAIQTNWR LSIILAGIFL FGAIIGGRLV FVQIFQYGFY KALAQGQQTL QTFSQGDRGR
IFAQDKAGNR YVLAMNQQRA FAFLSPAEMN LTEAEKEKFA EELASILMLE KAFVKGQLEK
DGSLYELLKR DLALGEQQSL ETLGYKGLYV GAETVRAYPQ EMMAAHVVGF TNTDGIGQYG
VEGYFDEELR GIEGIKMQAK NPAGYLLSVF RDTAQDGSDV ALTLDYNIQA EAEKLLKRGQ
EQLRIEGGSI VVMEPASGKI LAMASVPNFD LNNYGSVDDL KVFQNPVIQT VFEPGSIFKP
ITMAAALDEG VVTPETSYED TGIVEIGGRT VYNYDRHVWG RRTMTEVLQY SINTGAVFAE
RELGHRRFLQ YLEKFGFFEP TFISMAGEVA SANAEFQKGY EINFATAAFG QGIEMTQLQM
MRAFSALANN GILPQPFIVE GKREERQSGN VQVVSSKAAS EVTAMLVNVV QNGYGKSAGI
SGYWIAGKTG TAQVPWSALG INQSGYSDKT IQSFIGYAPA YSPRFLILVK LDNPAAQTAE
YSAAPIFRDM AKYIIEYYQI PPDYEVE
//
