ID A0A1G2R9R2_9BACT Unreviewed; 551 AA.
AC A0A1G2R9R2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Penicillin-binding protein transpeptidase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A3J68_01820 {ECO:0000313|EMBL:OHA69278.1};
OS Candidatus Wildermuthbacteria bacterium RIFCSPHIGHO2_02_FULL_48_16.
OC Bacteria; Candidatus Wildermuthbacteria.
OX NCBI_TaxID=1802453 {ECO:0000313|EMBL:OHA69278.1, ECO:0000313|Proteomes:UP000178529};
RN [1] {ECO:0000313|EMBL:OHA69278.1, ECO:0000313|Proteomes:UP000178529}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHA69278.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MHTY01000001; OHA69278.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2R9R2; -.
DR Proteomes; UP000178529; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 47..188
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 238..537
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 551 AA; 60829 MW; E8C0C80E59DB3346 CRC64;
MRAYIIFFLI LFVGASLMGR LLFLQVVKGG FYRALAQGQQ GSSLVEKGER GKIFARDKNG
SLVLLAANQK VPYAFVSPAE VESGNEELIA ETLASILGTE KANILLKTQN KESFFEIIKK
KITDEEAQRI EEKDIKGMHV GFETLRVYPQ GSFASHVLGF VNQDDKGQYG VESSYNEKLA
GKEGVKRNVF NPASYFLGDR SSNAKAGENI VLTIDYNIQS MAEALLKRVQ KELGVQEGTI
IVMDPRDGKI LSLANSPSFN PNEYAKESLE TFQNAALEKI FEPGSVLKAV TMASALQEGA
ITPETTYEDE GILRIGGYKI LNYDSRTWGK RTMREVLQFS INTGAVFAAE QLGFDRFMEY
LKKFGIFSKT FVDLPGEVFS QNKELQLGHE INFATASFGQ GVEMTSLQLM RAYAAISNGG
MLVTPYIVEQ KPNDPTGPIL SSKTVLDATS MLVGVMEEGY GKSARVPGYF IAGKTGTAQI
PWSALGIQKA GYSDQTIQSF IGYAPAYNPQ FLVLVKLNNP KTKTAEYSAV PLFRELTKYI
IDYLEIPPDY E
//
