ID A0A1G2S8Y7_9BACT Unreviewed; 360 AA.
AC A0A1G2S8Y7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN ORFNames=A3D51_02315 {ECO:0000313|EMBL:OHA81584.1};
OS Candidatus Yonathbacteria bacterium RIFCSPHIGHO2_02_FULL_44_14.
OC Bacteria; Candidatus Yonathbacteria.
OX NCBI_TaxID=1802724 {ECO:0000313|EMBL:OHA81584.1, ECO:0000313|Proteomes:UP000179118};
RN [1] {ECO:0000313|EMBL:OHA81584.1, ECO:0000313|Proteomes:UP000179118}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the radical SAM superfamily. Anaerobic
CC sulfatase-maturating enzyme family. {ECO:0000256|ARBA:ARBA00023601}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHA81584.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MHUT01000006; OHA81584.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2S8Y7; -.
DR Proteomes; UP000179118; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR43273; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR PANTHER; PTHR43273:SF3; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01216; thioether_bond_formation_requi; 1.
DR SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 1..227
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 360 AA; 40928 MW; 0578CD785A5A6880 CRC64;
MSAFQAKIVG DFCNIRCSYC RNRDFEQGVK SVMSIEKLER LFVFLNSQPQ KKLHVNWHGG
EPLLAGKDFF NKIVELEKLY PDKLWSNVVQ TNAILIDSGW AKFFSKNHFH VGVSVDGSEK
IHNHDRVGAT GKGTYQKVMR GVNMLRSYGI HPGTICTVTK KSVGFGKEMF LGLVNAGFKS
IAFNAFHNTA SESIGDLYGL SDKEWLTFLI EIFEEWVTLN DPTVRVRELD SMLAWIKSKS
ANCRVYRGTC HQWFAVDDIG DIYPCERLGK EIYFGNIDSI KTVEGLSTNP VYLKWKDSIV
ILHPKCQSCN LQSLCHNGCV SHRKSDNGDA PLYVYCESRL GFYNYLQSKL TETEKEKGHE
//
