ID A0A1G2TI19_9BACT Unreviewed; 422 AA.
AC A0A1G2TI19;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Serine--tRNA ligase {ECO:0000256|ARBA:ARBA00039158};
DE EC=6.1.1.11 {ECO:0000256|ARBA:ARBA00012840};
DE AltName: Full=Seryl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031113};
DE AltName: Full=Seryl-tRNA(Ser/Sec) synthetase {ECO:0000256|ARBA:ARBA00033352};
GN ORFNames=A3D49_02595 {ECO:0000313|EMBL:OHA96708.1};
OS Candidatus Zambryskibacteria bacterium RIFCSPHIGHO2_02_FULL_43_37.
OC Bacteria; Candidatus Zambryskibacteria.
OX NCBI_TaxID=1802749 {ECO:0000313|EMBL:OHA96708.1, ECO:0000313|Proteomes:UP000177279};
RN [1] {ECO:0000313|EMBL:OHA96708.1, ECO:0000313|Proteomes:UP000177279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- PATHWAY: Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec)
CC biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.
CC {ECO:0000256|ARBA:ARBA00005045}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHA96708.1}.
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DR EMBL; MHVS01000004; OHA96708.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2TI19; -.
DR Proteomes; UP000177279; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004828; F:serine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00770; SerRS_core; 1.
DR Gene3D; 1.10.287.40; Serine-tRNA synthetase, tRNA binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002317; Ser-tRNA-ligase_type_1.
DR InterPro; IPR015866; Ser-tRNA-synth_1_N.
DR InterPro; IPR042103; SerRS_1_N_sf.
DR InterPro; IPR033729; SerRS_core.
DR InterPro; IPR010978; tRNA-bd_arm.
DR NCBIfam; TIGR00414; serS; 1.
DR PANTHER; PTHR43697:SF1; SERINE--TRNA LIGASE; 1.
DR PANTHER; PTHR43697; SERYL-TRNA SYNTHETASE; 1.
DR Pfam; PF02403; Seryl_tRNA_N; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PIRSF; PIRSF001529; Ser-tRNA-synth_IIa; 1.
DR PRINTS; PR00981; TRNASYNTHSER.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF46589; tRNA-binding arm; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OHA96708.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 136..406
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 422 AA; 48137 MW; 8315EEDB4E1BD53E CRC64;
MLDIKFIREN KDAVQKAAKS KRLDFDVEKL IEVDNKRRKI LGHVEEKRAE QNVASNQIVK
STTEEREAIL EKMKILKAGL EQDEMELKEV MKEWQALMLQ APNIPDASVP EGESDADNKE
VKKWGEVPKF DFEPKNHIDI MAELGMADFE RGARVAGFRG YFLTASGAML TFAIWKYALD
FFLSRGFELM LVPSLVRKET LLGTGYLPQG EEDLYKTQDG EYLAGTGEVA TMSYHAGETL
PKEKLPRKIL AFSPCFRREA GSYSKDVKGL IRVHEFFKFE QVILCEASHE ESVKYHEELN
RNIEEFIESL KIPYRTVANC GGDLGLGQVK KYDVELWVPL ENTYREIGSA SYFHDFQTRR
LNIRYKDAEG KTQYAHSLNS TAIPTPRILV SLVENFQTAD GSVKIPEVLI PYMNGLAEIK
KV
//
