ID A0A1G2VAB2_9BACT Unreviewed; 453 AA.
AC A0A1G2VAB2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=VTT domain-containing protein {ECO:0000259|Pfam:PF09335};
GN ORFNames=A2854_00200 {ECO:0000313|EMBL:OHB18539.1};
OS Parcubacteria group bacterium RIFCSPHIGHO2_01_FULL_56_18.
OC Bacteria.
OX NCBI_TaxID=1817739 {ECO:0000313|EMBL:OHB18539.1, ECO:0000313|Proteomes:UP000177086};
RN [1] {ECO:0000313|EMBL:OHB18539.1, ECO:0000313|Proteomes:UP000177086}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the DedA family.
CC {ECO:0000256|ARBA:ARBA00010792}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHB18539.1}.
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DR EMBL; MHXD01000045; OHB18539.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G2VAB2; -.
DR Proteomes; UP000177086; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016791; F:phosphatase activity; IEA:UniProt.
DR Gene3D; 3.30.1240.20; -; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR032818; DedA.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR006379; HAD-SF_hydro_IIB.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR043169; PMM_cap.
DR InterPro; IPR032816; VTT_dom.
DR NCBIfam; TIGR01484; HAD-SF-IIB; 1.
DR PANTHER; PTHR30353; INNER MEMBRANE PROTEIN DEDA-RELATED; 1.
DR PANTHER; PTHR30353:SF0; TRANSMEMBRANE PROTEIN; 1.
DR Pfam; PF08282; Hydrolase_3; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..160
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
SQ SEQUENCE 453 AA; 49855 MW; 179FBBC29FB2F859 CRC64;
MFFGFDLIQA IQTLGYPGIF AIILAESGLF FGVSLPGGSL LFTAGLLASQ GILNIFILLA
TVITAAVLGD LIGYWFGAWI GPALYRRKDS RFFKQAHLRQ ASSFFEKHGA RTVLLARFIP
IIRTFTPIVA GIAGMKYRTF LTYNILGATL WGGGYTFLGY FLGEAVPSIE EYIVLIVLGI
MVVTFIPFVY HVWQEKKRAG TGAKPERLPA AVIFDLDDTL TESFTPPSEQ VLEKLFTLAE
RMPVAIISGA AFSRIERDIL KRVPHKADAS NLYVLSDNAA RCDVWKGDDW ETAYSFPLSS
DERSGIMEAI EEAVQETDIF AGEEPKYRII DRETSVAFAA LEDGASRSTK SAWDPQMIKR
PKLGNALQEK LPGYEVLIGG KTTIDIVRKG ISKAFGVEWL AKELNTPASD MLFIGDAFYE
GGNDAAVIPT GIRTHTTSGP EETDKLIDNM LNN
//
