ID A0A1G3KUM6_9SPIR Unreviewed; 618 AA.
AC A0A1G3KUM6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=PTS EIIA type-2 domain-containing protein {ECO:0000259|PROSITE:PS51094};
GN ORFNames=A2Y41_03365 {ECO:0000313|EMBL:OHD09009.1};
OS Spirochaetes bacterium GWB1_36_13.
OC Bacteria; Spirochaetota.
OX NCBI_TaxID=1802174 {ECO:0000313|EMBL:OHD09009.1, ECO:0000313|Proteomes:UP000177420};
RN [1] {ECO:0000313|EMBL:OHD09009.1, ECO:0000313|Proteomes:UP000177420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHD09009.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MIAO01000116; OHD09009.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G3KUM6; -.
DR STRING; 1802174.A2Y41_03365; -.
DR Proteomes; UP000177420; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR PANTHER; PTHR42770; AMINO ACID TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR42770:SF7; ARGININE_AGMATINE ANTIPORTER; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR Pfam; PF00359; PTS_EIIA_2; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 465..608
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
SQ SEQUENCE 618 AA; 68152 MW; 1779E35A8DDC6E09 CRC64;
MGLKRDLKLI DVFSIASGAM ISSGLFILPG IAFVKAGPGM IISYFLAGIL ALTGALSQSE
LVSAMPKAGG EYFYTVRSMG PAIGTINGMI SWFSITLKSS FSLIGMAAFV NILFHFNIEI
IAVVLTILFL ILNIIGVKEA GRFQVVLVIG LIGLLVFFVL NGINQVNADN LIPFAAKGWG
AVFSTAGFVF VSYGGLLKIG SVAEETQNPG RNIPLGMFLA LLVVGVLYTM VVFVTTGVLG
VNLVPDGIPT LMPISDAAEV FLGKPGKIAL SIAAVLAFVS TANAGIMAAS RYPMALSRDN
LLPLFFGKIS KKFGTPFLSI LLTGVIMALS FFLQLEFLVK AASTVILFNF ILSCLSVMIL
RFSKIQNYRP SFKSPLFPWI QIVGIGGFVF LIIEMGKEAL LMSLLMALAG LLVYLFYGRN
RSKKEYALLH LIERITNKAF VSRKLETELK EIIRERDNII QDRFDEIIEN SLVLDIENPM
TEEELFQFLA EKMSSRFHIS PEEFYRLLIE REKQSSTALT PYLAIPHIVI SGIKLFDIMM
VRLKKGVGFS AECPDIRAVF VLAGSQDERN FHLRAISAIA QIVQNKEFEK RWEKAKNIEE
LRDIVLLGKR HRHSGLEK
//
