ID A0A1G3MI13_9SPIR Unreviewed; 487 AA.
AC A0A1G3MI13;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Glutamate synthase (NADPH), homotetrameric {ECO:0000313|EMBL:OHD29322.1};
GN ORFNames=A2004_08250 {ECO:0000313|EMBL:OHD29322.1};
OS Spirochaetes bacterium GWC1_61_12.
OC Bacteria; Spirochaetota.
OX NCBI_TaxID=1802180 {ECO:0000313|EMBL:OHD29322.1, ECO:0000313|Proteomes:UP000178922};
RN [1] {ECO:0000313|EMBL:OHD29322.1, ECO:0000313|Proteomes:UP000178922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHD29322.1}.
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DR EMBL; MIAU01000096; OHD29322.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G3MI13; -.
DR Proteomes; UP000178922; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR006004; SudA-like.
DR NCBIfam; TIGR01316; gltA; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 35..147
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 167..474
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 487 AA; 51956 MW; EED7102315F139A5 CRC64;
MLSNAEILRD PSSLGPRERM AIAVQDMPCQ EPAIRATNME EVALGYSEEQ ARLEAARCLQ
CKTAPCIAGC PVGIDIPGFL AETVVGRYAE AAAIIRLTNL LPAICGRVCP QEVQCQAPCT
LGKALKSVDK AVQIGRLERF VADREREAIA GGAVVAAVSL APATGKRVAV VGSGPAGLTV
AADVRRAGHE VVIFEAFQKV GGVMVYGIPE FRLPKAIVRE EAAKLEAMGV RFELNTLVGR
TRPLQALLDE EGFDAVFVGV GAGLPKFMNI PGEILVGVFS ANEYLTRANL MKAWDRQKAA
TPLYPSQRVA VLGGGNVAMD AARMALRLGA AEVHVLYRRT RAEMPARAEE VGHAMEEGIQ
FQFLTNPVEI YGNGEGRVAG VVAQAYQLGE PDESGRRRPV AIPGSERKQD FDTVIVALGN
ESNPLLAKTT PGLKVDKWSH ILVDGEQRTS MDRIWAGGDI VLGAATVILA MGEGRRAAVS
INRFLAG
//
