ID A0A1G3P1V9_9SPIR Unreviewed; 364 AA.
AC A0A1G3P1V9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=HTH lacI-type domain-containing protein {ECO:0000259|PROSITE:PS50932};
GN ORFNames=A2096_17165 {ECO:0000313|EMBL:OHD48397.1};
OS Spirochaetes bacterium GWF1_41_5.
OC Bacteria; Spirochaetota.
OX NCBI_TaxID=1802188 {ECO:0000313|EMBL:OHD48397.1, ECO:0000313|Proteomes:UP000176667};
RN [1] {ECO:0000313|EMBL:OHD48397.1, ECO:0000313|Proteomes:UP000176667}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHD48397.1}.
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DR EMBL; MIBC01000383; OHD48397.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G3P1V9; -.
DR Proteomes; UP000176667; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00022475};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..68
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 364 AA; 40928 MW; 549FB9026603C2E2 CRC64;
MKKNTYKSII NMKEIARQAG VTRTTVSYVL NERYKKDLKI TDQVVQKVFA ISKKLGYRRN
ALACLIKKGN SNIIGFLGDI GEQGNAYMTG MLKGMTETLQ DNNYLLKLFS LTDQNFKELC
RQCVEQRLGG VICRLSDELK LEYLRREFAH YKIPVVLLGN SIQHDWCSRV ITDDISGITL
ALEHLVSLGH RKIGHLTIDV EMGLVIARRE GFIKGLKIAG IPFKKKSIFS IPPGFAMHKD
YYALFDNFFK SFKPTAVICA SDALAMKLEI WAYARGVRIP EALSITGFGN QDFSLLACPP
LTTIAQPMAL MGKRAAEIIL EIAEKKEISY SDELLPVKLV IRESTGLACD VSEQIIERAI
KKNH
//
