ID A0A1G3P295_9SPIR Unreviewed; 550 AA.
AC A0A1G3P295;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2096_09275 {ECO:0000313|EMBL:OHD48493.1};
OS Spirochaetes bacterium GWF1_41_5.
OC Bacteria; Spirochaetota.
OX NCBI_TaxID=1802188 {ECO:0000313|EMBL:OHD48493.1, ECO:0000313|Proteomes:UP000176667};
RN [1] {ECO:0000313|EMBL:OHD48493.1, ECO:0000313|Proteomes:UP000176667}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHD48493.1}.
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DR EMBL; MIBC01000381; OHD48493.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G3P295; -.
DR Proteomes; UP000176667; Unassembled WGS sequence.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169}.
FT DOMAIN 3..117
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 297..429
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT MOD_RES 52
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 550 AA; 61343 MW; 8A1D76CE06245D13 CRC64;
MKKAVILEYS GLLAGELEPV FAGHGVKLLH ETGGIPGISL IALKQPDLII IDSVLSDASG
VDILEFLKDA PEFSAIPVIV FSTVIDKNSS MFFFKADVFL HKEPDLPQKI LTSSLNLLEK
SSVPAAGFIL NKETITGKID SIRAERRTRE KLLEALLLIA CSALSVDTAI EKILDFLHTH
FAVKTVEYYC GPEKKLWGQE KGTADHEENI LLSLPRGQTA VLKVHHAENT SGLVRLGYFS
GLIKKIIEQI AVYEHNCKAA EKINLLFSSF LPQKVINSLL QKQHEQSLMT GEKRKITVLF
SHIRDFSHIE KNNSTEDVIA FLNRHFTGWS VRIKKHGGEI NKFIGDAVFA MFGAPESYED
NELRALSAAR EMLDFINEAN LKNFSFGPAG YRIGIGIHTG LAIIGNIGSS DNFDYTAIGD
TVNLAARLES LNKYYDTDIL LSAEVKAACC GNRYTEFREV DTVLVKGKDR PAVLFSLPGR
EFSDRQFFPV YRKGLTMFRL GNWHLAMDYF TECARLAPAD RITGIYLERC REFIKNPPAL
WNGAFSLGFK
//
