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Database: UniProt
Entry: A0A1G3PR24_9SPIR
LinkDB: A0A1G3PR24_9SPIR
Original site: A0A1G3PR24_9SPIR 
ID   A0A1G3PR24_9SPIR        Unreviewed;       751 AA.
AC   A0A1G3PR24;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   13-NOV-2019, entry version 10.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=A2Y33_09815 {ECO:0000313|EMBL:OHD56868.1};
OS   Spirochaetes bacterium GWF1_51_8.
OC   Bacteria; Spirochaetes.
OX   NCBI_TaxID=1802190 {ECO:0000313|EMBL:OHD56868.1, ECO:0000313|Proteomes:UP000177109};
RN   [1] {ECO:0000313|EMBL:OHD56868.1, ECO:0000313|Proteomes:UP000177109}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=27774985; DOI=10.1038/ncomms13219;
RA   Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA   Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U.,
RA   Brodie E.L., Williams K.H., Hubbard S.S., Banfield J.F.;
RT   "Thousands of microbial genomes shed light on interconnected
RT   biogeochemical processes in an aquifer system.";
RL   Nat. Commun. 7:13219-13219(2016).
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OHD56868.1}.
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DR   EMBL; MIBE01000013; OHD56868.1; -; Genomic_DNA.
DR   Proteomes; UP000177109; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000177109};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    296    314       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    357    381       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    435    463       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    469    488       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    526    545       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    690    709       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    721    741       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN       12    174       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   751 AA;  81902 MW;  6512BC0FCCB322AB CRC64;
     MPSKKSNTPK KTILIAVAGN PNCGKSTLIN AIAGSHLYVG NWPGVTVEKK EAQIEYGDYI
     LKFTDLPGTY SLTPHSDDER VAVDFLTAGR PDILLNVVDS TNLERNLTLT MHLLELEIPA
     VIALNMSDEA EKKGLIIDQE IVRSTLGAAV VKTSAVKKAG IASLLDTIVS VYEKKTPVNP
     AQSRYSQDIE LAAAGIESCL SSCYKGGAVF PLRWAALRLI ESDEFFLEKS GITDPESYIG
     TSLDHLHKAH RKNLLPLMDD ERFARANGLA QLALKKPPLS STELTDRIDK IALNRFLGIP
     LFLVSMWLMF KFTFDIGNPF VDWFDSIVTG PFSRWAQALL DLISAPAWLD SLIVDGIIAG
     VGGVLVFVPL IFLIMFFVTF LEGSGYMARA AFLMDGIMHK MGLHGKSFIP LVLGFGCNVP
     SVYATRILDD TKDKVITVMI SPLISCAARL PVYVLFAAVF FPVSMSGTVI WSLYLLGILL
     AFLMGWLLRK ILFKGETHEF IMELPPYRMP SLSNLLVHTW DKVKHFMVKA GTVILALTVI
     IWFMTKLPWG VEKTEDSFLG QAGKAIAPIF APLGFGNWQA SASLITGLGA KEVVVSTMAT
     IYVDDQAADM VLSNNAAGVL SNSMAESGTN TAPAPTFLQD LGEIGFGFLT ALKNAGLNLI
     SIFGIVTISA DEEAPSTELS AELHKTFTPL SAYAFLVFVL LYVPCITYLA AMKHELVKWK
     WVGITVVYQL TVAWVMAFII FQGGTLLGLG G
//
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