ID A0A1G3PRK6_9SPIR Unreviewed; 614 AA.
AC A0A1G3PRK6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=A2Y33_08395 {ECO:0000313|EMBL:OHD56970.1};
OS Spirochaetes bacterium GWF1_51_8.
OC Bacteria; Spirochaetota.
OX NCBI_TaxID=1802190 {ECO:0000313|EMBL:OHD56970.1, ECO:0000313|Proteomes:UP000177109};
RN [1] {ECO:0000313|EMBL:OHD56970.1, ECO:0000313|Proteomes:UP000177109}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHD56970.1}.
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DR EMBL; MIBE01000011; OHD56970.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G3PRK6; -.
DR STRING; 1802190.A2Y33_08395; -.
DR Proteomes; UP000177109; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 397..607
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 614 AA; 70095 MW; F3CB46A2C534EA18 CRC64;
MFLIDDAPLK SFLIDLISSL SPKYVLLFRD EVFSSVITES DLKRSGKLQV SDQIAEILKD
SPHRLALLLD DEHLKVWSEE NPELRRLLPH FNKLFDSSYK EMQAKSDEQS MIESAFSDLY
NAFAVNIGDE FLFSYLIGTI VKFLNAEVGL LQIFNENETL NFSMGFKAES LKNIKMDGKE
FRDYLYNTKE ILLIDSVVRE NRLSVADSDR QHLKTILAVP IFNKGVLVAI IYLVNKSYSA
VNESFTGADK RFIANLSIQI GAIITNALLY KKTIELKEFN EEVLENIPVG ILNSSTDGTT
LFTNRYMREL VYSMNMSIEA VIGLIESYNL PEFFGKELHI QRAERDFYLS VSKRILNIGF
KPVVNLYTVF DITDEKEIEG QLRKSEKLAS AGELISSIAH EIKNPLTSIK GFADLLWQRI
HDEEFVLKFA NIVSREINRL NNIIERFLSF AKPQIGVLAT IDLNAIIHEV SEVIAYSLKE
SDVSLVMNMK EDIIVYGNRE LLSQVFMNIV LNSIQALREI KRKKKTIRID EEIVSGFAEI
VIEDNGEGIK KEDLDKVFNP FYTTKSKGSG LGLSISHRIV TEHKGTLLID SKEGEYTRLI
IRLPVFEKSR IEEK
//
