ID   A0A1G3PZ87_9SPIR        Unreviewed;       620 AA.
AC   A0A1G3PZ87;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=DNA helicase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=A2096_09190 {ECO:0000313|EMBL:OHD59744.1};
OS   Spirochaetes bacterium GWF1_41_5.
OC   Bacteria; Spirochaetota.
OX   NCBI_TaxID=1802188 {ECO:0000313|EMBL:OHD59744.1, ECO:0000313|Proteomes:UP000176667};
RN   [1] {ECO:0000313|EMBL:OHD59744.1, ECO:0000313|Proteomes:UP000176667}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=27774985; DOI=10.1038/ncomms13219;
RA   Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA   Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA   Williams K.H., Hubbard S.S., Banfield J.F.;
RT   "Thousands of microbial genomes shed light on interconnected biogeochemical
RT   processes in an aquifer system.";
RL   Nat. Commun. 7:13219-13219(2016).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|ARBA:ARBA00001665};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OHD59744.1}.
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DR   EMBL; MIBC01000170; OHD59744.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G3PZ87; -.
DR   Proteomes; UP000176667; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   CDD; cd17920; DEXHc_RecQ; 1.
DR   Gene3D; 1.10.10.1390; ATP-dependent DNA helicase RecQ; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR029491; Helicase_HTH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR032284; RecQ_Zn-bd.
DR   NCBIfam; TIGR00614; recQ_fam; 1.
DR   PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR   PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF14493; HTH_40; 1.
DR   Pfam; PF16124; RecQ_Zn_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          34..203
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          230..377
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   620 AA;  70605 MW;  D8DECC8333E9CED4 CRC64;
     MYIILIKKII QMPEKYLKEY FHFREFRPGQ KEIIETILEG RDVAALMPTG GGKSLCYQLP
     AVVSGKLSIV ISPLIALMKD QVEALKARGI PAAFINSSLS YNEIYACLNE ARMGKIRILY
     VAPERFRNKE FCSFFCTLDI FLLAVDEAHC LSQWGHDFRP DYLKIRDYIG MLERRPVIAA
     FTATATPEVK DDIIARLDLH APRVFIRGFD RPNLYFLVQY NMKSKDRYAE ILRIISSLSG
     SGIVYALSRK ETEVIAGYLC AHGIPTMSYH AGMDGAARDK IQNDFMENKF RVIAATIAFG
     MGVDKSDIRF VIHSGMPGSL EGYYQEAGRA GRDGEKAYCV LLHSGKDETT HKFFLRKSRE
     AMEAQGKDHW EITRLLSVKY HRLGKITEYA EKIKCRRQMI LEYFGDPEAG RHNDNCSGCD
     VCLGWKRRIK KHTLKIPEPS GHGLISATIK ETVRLYEEKF DVQKIAKMRG LSAATITGHL
     ISWYEAGGCL AVNDFVSADE EKQIAWAFEK TGMDKLKPVK ELLPKEISYE KIRFMAIKIR
     REKAGHQEIK RQTYNVEQIR KRYPGAYLKW SGEDDAELMK EASRGTAVHD LARIFQRNTG
     AIRSRLRKLG IGKKPDSSGK
//