ID A0A1G3R0D0_9SPIR Unreviewed; 350 AA.
AC A0A1G3R0D0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 13-SEP-2023, entry version 17.
DE SubName: Full=Threonine aldolase {ECO:0000313|EMBL:OHD72308.1};
GN ORFNames=A2V99_13925 {ECO:0000313|EMBL:OHD72308.1};
OS Spirochaetes bacterium RBG_16_67_19.
OC Bacteria; Spirochaetota.
OX NCBI_TaxID=1802196 {ECO:0000313|EMBL:OHD72308.1, ECO:0000313|Proteomes:UP000177018};
RN [1] {ECO:0000313|EMBL:OHD72308.1, ECO:0000313|Proteomes:UP000177018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the threonine aldolase family.
CC {ECO:0000256|ARBA:ARBA00006966}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHD72308.1}.
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DR EMBL; MIBK01000189; OHD72308.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G3R0D0; -.
DR STRING; 1802196.A2V99_13925; -.
DR Proteomes; UP000177018; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR CDD; cd06502; TA_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR023603; Low_specificity_L-TA-like.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; NF041359; GntG_guanitoxin; 1.
DR PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF017617; Thr_aldolase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
FT DOMAIN 8..290
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 203
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ SEQUENCE 350 AA; 37654 MW; CA6CFF0EFBBA474C CRC64;
MSAVLPIDLR SDTVTRPTQA MRRAMSEAEV GDDVLGEDPT VNTLEAEAAE RLGKEAALLV
PSGTFGNQLA LFTHCPRGSE VVLSDDSHIV QHEAGASAII AGVQLRVFNP ADGLPRWEEI
RARIRYSDDI HVPPTSLVAL ENALSNGMVM SLEEMEKIGG GARACGVPVH VDGARIFNAA
TSLGLEASAL AAPADSVMFC LSKGLCAPVG SLLTGRRAFI ALARRRRKIM GGGMRQAGVL
AAAGLVALRQ MTLRLAEDHE KARLLGEAFA KTGLFEVAPY PVRINMLFVR FRGEHAGREA
RLVEELARRG VWSYPPFDGW IRFVTHHDVP PERLQKACRI VEEAAAAAVA
//
