ID A0A1G3XWI4_9PROT Unreviewed; 385 AA.
AC A0A1G3XWI4;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 13-SEP-2023, entry version 16.
DE SubName: Full=Exosortase A {ECO:0000313|EMBL:OHE56725.1};
DE Flags: Fragment;
GN ORFNames=A2X71_03355 {ECO:0000313|EMBL:OHE56725.1};
OS Thiobacillus sp. GWE1_62_9.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Thiobacillaceae; Thiobacillus.
OX NCBI_TaxID=1802374 {ECO:0000313|EMBL:OHE56725.1, ECO:0000313|Proteomes:UP000178291};
RN [1] {ECO:0000313|EMBL:OHE56725.1, ECO:0000313|Proteomes:UP000178291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHE56725.1}.
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DR EMBL; MIDJ01000208; OHE56725.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G3XWI4; -.
DR STRING; 1802374.A2X71_03355; -.
DR Proteomes; UP000178291; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR InterPro; IPR013426; EpsH-like.
DR InterPro; IPR026392; Exo/Archaeosortase_dom.
DR InterPro; IPR019127; Exosortase.
DR InterPro; IPR017540; Exosortase-1.
DR InterPro; IPR014263; Methanolan_biosynth_EpsI.
DR NCBIfam; TIGR02602; 8TM_EpsH; 1.
DR NCBIfam; TIGR04178; exo_archaeo; 1.
DR NCBIfam; TIGR03109; exosortase_1; 1.
DR Pfam; PF11984; DUF3485; 1.
DR Pfam; PF09721; Exosortase_EpsH; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 311..385
FT /note="Methanolan biosynthesis EpsI"
FT /evidence="ECO:0000259|Pfam:PF11984"
FT NON_TER 385
FT /evidence="ECO:0000313|EMBL:OHE56725.1"
SQ SEQUENCE 385 AA; 42617 MW; 80F38A908999A45F CRC64;
MSALPDSLPA APRADWLLPG ALTAGVLLIL AGLFWPTFHS MIEVWERSET FAHGYLIFPI
SAWLIWRQRD ELARVQPRPD LRGLILLAVV GAGWMLADAG SVNVVAQYAF IAMLIAAIWA
LLGWTFVWTA FFPLMFLFFA VPVGEFLIQP LMGVTADFTV AMLQATGIPV YREGMFFSIP
SGDWSVVEGC SGLRYLIASV TLGVLYAYLT YRSWKRRLLF SIAAVVVPVF ANSGRAYMIV
MIAHLSDMKL ALGVDHYIYG WAFFGLVMLL LFWIGGFWRE DGQATPAQPE HGKLPADRAG
TRPILLVAVA ALVVAGLWPA YAAWLSARPL PAMPELQIEA QGGWQPAASF TGWAPHWVGA
DRQVRQSYSQ AGRQVMLELN YYVTQ
//
