ID A0A1G4AP64_9PEZI Unreviewed; 1104 AA.
AC A0A1G4AP64;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=alpha-mannosidase {ECO:0000256|ARBA:ARBA00012752};
DE EC=3.2.1.24 {ECO:0000256|ARBA:ARBA00012752};
GN ORFNames=CORC01_13786 {ECO:0000313|EMBL:OHE90901.1};
OS Colletotrichum orchidophilum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum.
OX NCBI_TaxID=1209926 {ECO:0000313|EMBL:OHE90901.1, ECO:0000313|Proteomes:UP000176998};
RN [1] {ECO:0000313|EMBL:OHE90901.1, ECO:0000313|Proteomes:UP000176998}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMI 309357 {ECO:0000313|EMBL:OHE90901.1,
RC ECO:0000313|Proteomes:UP000176998};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHE90901.1}.
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DR EMBL; MJBS01000214; OHE90901.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G4AP64; -.
DR STRING; 1209926.A0A1G4AP64; -.
DR OrthoDB; 2786490at2759; -.
DR Proteomes; UP000176998; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR041147; GH38_C.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF17677; Glyco_hydro38C2; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000313|EMBL:OHE90901.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000176998}.
FT DOMAIN 570..649
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1104 AA; 123592 MW; 3488518053304C9E CRC64;
MCGQDGNCGS GSSSSTPSYP LRAPVPVGKR ANKLYRDRTA NFYSPGQWEK VNLLSMMHLA
VRSDPSVINL SVWHSPGLSR PTFADATASA NDYRPSQVGD SFGPSWSTHW FRVRVTIPEE
MQQMEHLELH WDCSNEATVW TAEGQPLQGL TGRGERIEWI LPASFKDGRE HVFFLEMACN
GMLTNAAGEP IFKNNANGDA IQPPDPNKSF SLTKAEIVAV DRQARALHAD ITVIHQAAEE
FPEDSWEQHE ALNVATRIIN AFRVGDRESI VKSRKIAEEY LGPNVNSANV FNGGGDKGSS
VLAIGHCHID TCWLWPWEET KRKVARSWLN QCDLMDRYPE LNFACSQAQQ FKWLKQGYPY
AWERVQAKVE AGQFHPIGGC WVEHDTNIPS GESLIRQFLF GQRFFESNFG RRSTTCWLPD
TFGQSSQMPQ LCRQAGMNRF LTQKICFNNM NEFPHTTFNW VALDGSQVIC HMPPAKTYCA
NATFGDVKRS MTQHKSLDQD HTSLLVLGKG DGGGGPTWQQ LESLRRLRGL SDTTGLLPRV
HSGGNPDDFF DRLEKKAQTL PTWHGELYFE LHRGVYTTQA QTKLNNRKAE ILLRDVELLA
TIASVEEKSY RYPKRELDEM WEGVLLCQFH DCLPGTAIGM CYDDSDKVYA NVYDIGNTLL
RSIYSVLKVN DTNDKPAETN KLVALNTLGW PRKEVVTDED GKDIIAQGTG NIISAQEVTH
TDTKHLVTVK EVSTGIFVLE NSRFTVTVDK GCITSLYDRR AKREAIAPGS KANQYVIFDD
KPIYWQAWDV EVFHLDTREE LQGSQTYALG SSPLRASVVT ETRISDVSSI RTTVSLAAAF
DGDESGTGVE CTAEVDWHET MKFLKVEFPV DVRHHEASYD TQFGVIRRPT HYNTSWDMAK
FEVCCHKYAD LSEYGYGVSI LNDSKYGFAT VGNTMRLSLL RSSKAPDDGA DMGKHVIRWS
ILPHRGPLGP ETVRAAFEFN NPLKLVSASA DCPLLTTGAG AGTFPVALTG DENLVLDTIK
RGEDDEDVGL GELPVRRGRS VVVRVYESLG GRGRGKVVTR WEVRSVHKTN LLEDDEEEVR
VDDGGFEVDL GPFQLQTYRL ELVD
//
