ID A0A1G4BG83_9PEZI Unreviewed; 1002 AA.
AC A0A1G4BG83;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=RasGEF domain-containing protein {ECO:0000313|EMBL:OHF00389.1};
GN ORFNames=CORC01_04370 {ECO:0000313|EMBL:OHF00389.1};
OS Colletotrichum orchidophilum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum.
OX NCBI_TaxID=1209926 {ECO:0000313|EMBL:OHF00389.1, ECO:0000313|Proteomes:UP000176998};
RN [1] {ECO:0000313|EMBL:OHF00389.1, ECO:0000313|Proteomes:UP000176998}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMI 309357 {ECO:0000313|EMBL:OHF00389.1,
RC ECO:0000313|Proteomes:UP000176998};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHF00389.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MJBS01000028; OHF00389.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G4BG83; -.
DR STRING; 1209926.A0A1G4BG83; -.
DR OrthoDB; 4819765at2759; -.
DR Proteomes; UP000176998; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00882; Ras_like_GTPase; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR001806; Small_GTPase.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF348; GUANYL-NUCLEOTIDE EXCHANGE FACTOR RASGEF, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04700)-RELATED; 1.
DR Pfam; PF00071; Ras; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000176998}.
FT DOMAIN 514..640
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 747..985
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 651..679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 684..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..157
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..411
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..668
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1002 AA; 112461 MW; 3F8A06DBC09C6B3E CRC64;
MASDPMGARK AHRSSEGSHI PPKYYHGERS TAAAAAFSSS RRTDRDAAHR SAPAAPKRHT
PHYAVHRESS IEPIRPSASE QPANYRDSFI SIVDDPFFLR FDDNNIEGAL ALDPRWTATS
FDDADAEDEG EEDEGDENEN ENENVGDSQE DEDEEEEFDF DAFEFRDDDT PNERWPPPRR
ESLIIGHSLY WQPPTSAIME SLNIAVIGAS GVGKSSFVQR VLGLSRPPIT NASSVRMVVD
NVTYGVTLIE LDLEYFELNP LQPIQWPKQI NGHIVPRVDG ALIIYDVMNK ESMKELPQTI
AALTKSGLPA VLVANKCDHP ESERQVDSQR VASHEYFKSC VGVFNLSTSS PERARACLNT
TLKASIAYRK ESQVESGVPR RRAASAANLE AHDSSNGRPL SQQSKHSRAS SDLSLLRGVP
PPIPDHLRGP LPPRSPRIAD FGGAPSSSGS FGPSDTIEEE SQQTVSSQLR TPGIRLDRGP
TDSFLDMDES DAESFRYSEE VPILQRSDES FLEKPTKSAG VAFDELVDRL IAPRMTKADN
NFSDVFLCLY RKFAAPGELF SAILTRLDRV RDDKSAHYLS KTATQLRIIE VVAKWVSLYP
GDFARSGTRR NLEEFIKHLS TEPIFSIAAQ QIRRHLEFSV VEDDNTGWAK SDELADEEGS
KVLSKEKTRS TSDMSNGMVS LTIDDDRTTD ERPSGSSDFS QVDRTSTVGT TVSFHSYDEY
EREAANMEPT DVLPMNKFRY HIFMDITDDD IADEMTRIDW VMFSSIRIRD FVRHVSLSLE
QRSKCKSLKN VNRMINHFNH VAKWVANLIL LRDKAKHRSQ MLEKFMNIAQ KLRRLNNYNG
LAAVLAGING TAVHRLAQTW ALVPLEAQKS FAKLGILMGT QKSHFAYRLA WENSPLPRIP
YIPLHRRDLV SAEEGSKTFV GPEGDRVNWK KFEVLGEVLL PLMKSQGTAY PNLSKHEAAR
ELILDCRMPT DEEEIYQRSV QLESTAGGGA EYNKKKFPWF AK
//
