ID A0A1G4BH50_9PEZI Unreviewed; 1115 AA.
AC A0A1G4BH50;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=DSHCT domain-containing protein {ECO:0000313|EMBL:OHF00724.1};
GN ORFNames=CORC01_04041 {ECO:0000313|EMBL:OHF00724.1};
OS Colletotrichum orchidophilum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum.
OX NCBI_TaxID=1209926 {ECO:0000313|EMBL:OHF00724.1, ECO:0000313|Proteomes:UP000176998};
RN [1] {ECO:0000313|EMBL:OHF00724.1, ECO:0000313|Proteomes:UP000176998}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMI 309357 {ECO:0000313|EMBL:OHF00724.1,
RC ECO:0000313|Proteomes:UP000176998};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. SKI2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010140}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHF00724.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MJBS01000025; OHF00724.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G4BH50; -.
DR STRING; 1209926.A0A1G4BH50; -.
DR OrthoDB; 1352at2759; -.
DR Proteomes; UP000176998; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd18024; DEXHc_Mtr4-like; 1.
DR CDD; cd13154; KOW_Mtr4; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 2.40.30.300; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000176998}.
FT DOMAIN 183..339
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 453..625
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..417
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1115 AA; 126064 MW; E8DF2623918CE602 CRC64;
MDELFDVFNA QPDAQSESHS EPEHETEVVD PPQKSRKKDK KSKKRKADGG IKNGVAEQPE
DDDMPDADET SKDGKDAEEA EDAAASSDEQ QEPHKDKRRK KEDEAQPVLT DTFQTAQSRE
VAGAAVFTPA QDESLVLSHN IQHQVALPPD LDYEYVPLSE HKPPAEPARQ YSFKLDPFQA
LSVASIEREE SVLVSAHTSA GKTVVAEYAI AQCLKRNQRV IYTSPIKALS NQKYRDFEAL
FGDVGLMTGD VTINPTASCL VMTTEILRSM LYRGSEIMRE VAWVVFDEIH YMRDKTRGVV
WEETIILLPD KVRYVFLSAT IPNAFQFAEW IAKIHHQACH VVYTDFRPTP LQNYFFPAGG
SGIFLVVDEK GVFREGNFQK TMALIEAGKG QDPNNANASW KGKGAKKQTQ KGGQASDMKS
DISKIIRMIM QKSFHPVIVF NFSKKEVENL ALQISHFQFN NDSEQAMVKT VFNNAIQSLS
EADRELPQIQ NLLPLLQKGI GVHHSGLLPI LKETIEILFQ ESLIKVLVAT ETFSIGLNMP
AKTVVFTQTN KWDGVQRRPL TPSEYIQMSG RAGRRGLDTR GIVIMMIDDK MEPDTARGMV
VGEQDRLNSA FYLGYNMILN LLRIEAISPE FMLERCFHQF QTGASVPALE RDLVALQQER
DSMSIADEAT VKDYYNLRNQ LEQYTSDMRA VIQHPEHCTD FMQPGRLVRI HDPKKTNNTI
GGTDFGWGVV ANLIRRDRNR KPGEPEYPPQ ESCLIDVMMV VDQKSAPIAE GSRHLTSDLP
SGLVPYSNPE QPDNGARFEI IPCLLTCVKT ISQIRVFMPK DCKSQSALNE VGNSLREVHR
RFPDGLPILD PVENMGITDE SFRALMRKIE MLEARLLTNP LHGSPLLPEL YLQYRAKEKL
GEQIKSKKKE IARLHSIAQM DELKARKRVL RRLGFLNESE VVELKARVAC EISSTEGHEL
VLAELLFDRF FNELSPELIA ATLSCFVLDE KLETAQLREE LAKPYREVQA KAKQVAKVSR
ESKLELNEEE YLAGFKWQLM ETVYSWAQGK PFADICKMTN AYEGSLIRLF RRLEELLRQM
GQGAKVMGSD ELTQKFEDSL AKIRRDIVAA QSLYL
//
