ID   A0A1G4FKP1_9FIRM        Unreviewed;       443 AA.
AC   A0A1G4FKP1;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Permease IIC component {ECO:0000256|PIRNR:PIRNR006351};
GN   Name=licC_1 {ECO:0000313|EMBL:SCL87419.1};
GN   ORFNames=PP176A_1292 {ECO:0000313|EMBL:SCL87419.1};
OS   Sporanaerobacter sp. PP17-6a.
OC   Bacteria; Bacillota; Tissierellia; Tissierellales; Sporanaerobacteraceae;
OC   Sporanaerobacter.
OX   NCBI_TaxID=1891289 {ECO:0000313|EMBL:SCL87419.1, ECO:0000313|Proteomes:UP000179042};
RN   [1] {ECO:0000313|EMBL:SCL87419.1, ECO:0000313|Proteomes:UP000179042}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PP176A {ECO:0000313|EMBL:SCL87419.1};
RA   Seilhamer J.J.;
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC       system (PTS), a major carbohydrate active -transport system, catalyzes
CC       the phosphorylation of incoming sugar substrates concomitant with their
CC       translocation across the cell membrane.
CC       {ECO:0000256|PIRNR:PIRNR006351}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FMIF01000013; SCL87419.1; -; Genomic_DNA.
DR   RefSeq; WP_071139619.1; NZ_FMIF01000013.1.
DR   AlphaFoldDB; A0A1G4FKP1; -.
DR   Proteomes; UP000179042; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR004501; PTS_EIIC_3.
DR   InterPro; IPR004796; PTS_IIC_cello.
DR   NCBIfam; TIGR00359; cello_pts_IIC; 1.
DR   NCBIfam; TIGR00410; lacE; 1.
DR   PANTHER; PTHR33989; -; 1.
DR   PANTHER; PTHR33989:SF11; LICHENAN PERMEASE IIC COMPONENT; 1.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   PIRSF; PIRSF006351; PTS_EIIC-Cellobiose; 1.
DR   PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006351};
KW   Reference proteome {ECO:0000313|Proteomes:UP000179042};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006351}.
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        71..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        144..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        227..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        294..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        351..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        390..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          8..419
FT                   /note="PTS EIIC type-3"
FT                   /evidence="ECO:0000259|PROSITE:PS51105"
SQ   SEQUENCE   443 AA;  48819 MW;  0940629CEA39CFED CRC64;
     MSKRMDSLEN KLMPVADKFA NNRYLLAIRD GFMLTMPLLI IGSIFMLLAY LPITGYDAFM
     ARVFGENWMD FFSVAYNTTM SIMTIFVIIG ISGSLSDYYK LERLNTAVIS LVAFFILTPF
     VTSFTPEGMD QTFKVTGIIP TEWIGAKGLF AGMLTAILST EIVRWVTKKG WVIKMPAGVP
     PTVGKAFSSL IPAAITIIIF DIIRLIFAFT PFETIHNFIY SILQVPLTSL GDTLGAALIA
     NFFVGLFWIF GIHGADIVQS VMNPIWIALA TENLAAYQAG SELPHIITQQ FNQIYLWMGG
     GGATLGLCLA MLFVCKSQQC KKLGKLSIFP GIFNINEPII FGLPVVLNPM MIIPFIITPL
     VLCLVCYGSM AIGLVPKPNG VLVPWTTPPI IGGFLCGGIR GALLQIVGLI ISFFIYLPFI
     KTVDKQYLEQ EKSYNATPED NIN
//