ID A0A1G4FNS0_9FIRM Unreviewed; 278 AA.
AC A0A1G4FNS0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Pur operon repressor {ECO:0000256|ARBA:ARBA00018449};
GN Name=purR_2 {ECO:0000313|EMBL:SCL95477.1};
GN ORFNames=PP176A_2869 {ECO:0000313|EMBL:SCL95477.1};
OS Sporanaerobacter sp. PP17-6a.
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Sporanaerobacteraceae;
OC Sporanaerobacter.
OX NCBI_TaxID=1891289 {ECO:0000313|EMBL:SCL95477.1, ECO:0000313|Proteomes:UP000179042};
RN [1] {ECO:0000313|EMBL:SCL95477.1, ECO:0000313|Proteomes:UP000179042}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PP176A {ECO:0000313|EMBL:SCL95477.1};
RA Seilhamer J.J.;
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC family. {ECO:0000256|ARBA:ARBA00008391}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FMIF01000038; SCL95477.1; -; Genomic_DNA.
DR RefSeq; WP_071141118.1; NZ_FMIF01000038.1.
DR AlphaFoldDB; A0A1G4FNS0; -.
DR Proteomes; UP000179042; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0045982; P:negative regulation of purine nucleobase metabolic process; IEA:InterPro.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR015265; PuR_N.
DR InterPro; IPR010078; PurR_Bsub.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01743; purR_Bsub; 1.
DR PANTHER; PTHR43864; HYPOXANTHINE/GUANINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43864:SF2; PUR OPERON REPRESSOR; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF09182; PuR_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000179042};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 5..74
FT /note="Bacterial purine repressor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09182"
FT DOMAIN 111..250
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 278 AA; 31455 MW; 3E643868137412A1 CRC64;
MKKLKRNERV AGIMYILTTK PNYVFSYRYF CELFDVKKSS ISGDISIIKE LVEKIEIGTI
ETITGSGGGV KFAPKVQKEK TKYFLEQLCK DLSEPNRIIS GGFIYMLDIL YSPHIVKELG
IIFANEFMDK GIDYVVTIET KGIPIALMTA EILNVPLVII RKNIKVTEGS TVNINYISGS
TKIIQTMSLS RKALREMSKV LIIDDFMKGG GTVRGIYEMM EEFNVEVAGT GVLISTMSPE
KKLVNNYTSL MILKDVDEEN RKIDLISNFE YLNHIKKN
//
