ID   A0A1G4IZH7_9SACH        Unreviewed;       349 AA.
AC   A0A1G4IZH7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=LADA_0C04918g1_1 {ECO:0000313|EMBL:SCU82393.1};
GN   ORFNames=LADA_0C04918G {ECO:0000313|EMBL:SCU82393.1};
OS   Lachancea dasiensis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=1072105 {ECO:0000313|EMBL:SCU82393.1, ECO:0000313|Proteomes:UP000190274};
RN   [1] {ECO:0000313|Proteomes:UP000190274}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Devillers H.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004406}.
CC   -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC       {ECO:0000256|ARBA:ARBA00009219}.
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DR   EMBL; LT598459; SCU82393.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G4IZH7; -.
DR   STRING; 1266660.A0A1G4IZH7; -.
DR   OrthoDB; 1133at2759; -.
DR   Proteomes; UP000190274; Chromosome C.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   CDD; cd09813; 3b-HSD-NSDHL-like_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR   PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000190274}.
FT   DOMAIN          9..279
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   349 AA;  38096 MW;  6EA7EA259EA60E48 CRC64;
     MSGLNSVLLV GGAGFLGLHL IEKFYNLSPR PDIHVFDVRP LPDNLSSQFT FDPKAVTTHI
     GDLTSENDVK CALQSSQADV VVHSASPMHG CSQEIYNKVN VAGTKNLLET SKRLNVKAFI
     YTSSAGVIFN GQDIHNADET WPIPEVPMDG YNETKAIAEE MVLKSNSISQ SFVTIALRPA
     GIFGPGDRQL VPGLRSVAKM GQSKFQIGDN NNLFDWTYVG NVADAHVLAA EKLLLKSSQP
     EVAGEAFFIT NDSPAYFWAL ARTVWRADGH VDKYNIVLNR PIAICAGYLS QCISKLTGKE
     PGLTPFRVKV VCAVRYHNVN KAKRLLGYKP AVGIEEGIAK TLAWMNETS
//