ID   A0A1G4J1N9_9SACH        Unreviewed;      1540 AA.
AC   A0A1G4J1N9;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=LAMI_0C02564g1_1 {ECO:0000313|EMBL:SCU83258.1};
GN   ORFNames=LAMI_0C02564G {ECO:0000313|EMBL:SCU83258.1};
OS   Lachancea mirantina.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=1230905 {ECO:0000313|EMBL:SCU83258.1, ECO:0000313|Proteomes:UP000191024};
RN   [1] {ECO:0000313|Proteomes:UP000191024}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Devillers H.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT598466; SCU83258.1; -; Genomic_DNA.
DR   STRING; 1230905.A0A1G4J1N9; -.
DR   OrthoDB; 12619at2759; -.
DR   Proteomes; UP000191024; Chromosome c.
DR   GO; GO:0015629; C:actin cytoskeleton; IEA:UniProt.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:UniProt.
DR   CDD; cd21206; CH_IQGAP; 1.
DR   CDD; cd12206; RasGAP_IQGAP_related; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR000593; RasGAP_C.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR14149:SF14; PATTERNED EXPRESSION SITE; 1.
DR   PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR   Pfam; PF00307; CH; 1.
DR   Pfam; PF00616; RasGAP; 1.
DR   Pfam; PF03836; RasGAP_C; 1.
DR   SMART; SM00033; CH; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50021; CH; 1.
DR   PROSITE; PS50096; IQ; 2.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000191024}.
FT   DOMAIN          130..240
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          914..1108
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          297..349
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          802..829
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        297..314
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        315..331
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1540 AA;  174859 MW;  A7CB8D65B2488F4F CRC64;
     MASIVESPSR ARNAFLDRYI TTLKDDGRSV LKPVSPSRIN KTPQSREIKQ FSRLDDNDVL
     FDENALREST SRKSQKASKL EFLALSPQKT SIGPSEYSND QISSISASNS GHVFDVKSLS
     SRDAKYYEFM CRVAEAKDWI ECIIKEETAS VADLASGAVM RDGVFLAKLT QAINPSLVKK
     IVGPSKTLNY THTQNINAFF TLVESAGVPE LFRFELTDLY DRKDIPKVFE TIHALANIIS
     KKWPGQAPEI KNLSGRITFG QDELKACQRR YPTIHNFRSF KATNSVINVS PNRNGSKGLI
     TDFSSPASFD KSPQRSPRVN KEVKRISDDP ASVDGVDLPV TPTTPTPHRE KQLDFQLPKE
     GHLGQLQASS ENAFSRNLQD TAPSLTYSGS FSPEKSLLYY SPTISRHLSY DTGNWASKGS
     AIDFYDTATY SKPFYSPTRQ KRMNELEFLD MINCIQAICR GVNLRFNLLM RKRKFEIVSE
     TVQRIQASAR GMLTRKSFGG RIKISTQEDV CTNIMNFQAI MRGKCQRDKF YEIRFNLVKF
     ESALLRFQNR CCCAARRKKY ARLSEGIGFT RQPLAYFQSI LKGKAMRLKL AAKLNPRSED
     RHGVVKFQSF VRGIELRKSK NTSMLELHAE FSVLVQFQAL IKGFSKRRHL ATIKSGLGRE
     FTNLQLFVCV LKARQERLRI SQVTRSVKAK EDPISYLQAN IKGVLARYAL ELIDGFVEYH
     SHNEIISTIR GALVRARLRK MNLYYVQHTK SIIKLQSKIR ACRLRWAYLE FMSSGNPSLW
     SVKRFAHLLN QIYTSHESQS DLEELKSMID LKNKEKGKLE AHLQRLNAKR LILAQNRILV
     NTTSTGPDFD IMLANVESTF PFYGKIFYLL QADSFYWKLL FQIDRSFSMK YVSKSFSWVN
     GRMNRREQVF FVKLVADIMD SEIEKVAEVT AVIGDSEPTT HCYSELLGFY ASHQIPDLLL
     GIIQPALEYL DNPHVSFEFI PSEIYKEMSS EHLSISSSEA IGIPEVKEIF IKNLMDIWAS
     LELIKEGIER LISKPPDDLK YLCTKAYHCV ADRSSSEEDA LLAISHILID TFVARSLKDT
     AKFGLKLNSP DGEKKLSTLA FVVKRVFSFQ IFEGYLSPLN QYSEQIRPDI VMIHRSMLTS
     PVFESNRDKL LYYDMYQDKR PTLSISRQYI LDITTMLERN AASFPHDDPL HALLKGIRDN
     GELRAMQAYH QNLLLLNLDS TALALSSSDQ RLCSIYNEIK RGLTYMMQVE DVDTNLYDLL
     TGSVLEKDEP VFQKLLKASP AIKRDPLMKE LKELSYFALK EHVLERTCEF KRMNDMPAND
     SLQGVLNDIA NTIKSRDFVK NNVTVEVQIA NKTLEEIGIS CSKLQKTSKA LEGSIRQAIQ
     NAQRGSNFEA PRKHGFGNKL KSAYKKVQTK SSKSSSGLSF QYTARQLYEH GALLKIDDEK
     LGKAAVAFFG SSGPKFPDIQ FKISTSDGET FSVEMTDQRK SGNKLSITKM DTIALTKLLD
     LATDGKQSHV NLIAKKITLD ASKFLGLLTE TFFKRLNASR
//