ID   A0A1G4JCR1_9SACH        Unreviewed;       212 AA.
AC   A0A1G4JCR1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   13-SEP-2023, entry version 22.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 20 {ECO:0000256|RuleBase:RU364152};
DE   AltName: Full=Mediator complex subunit 20 {ECO:0000256|RuleBase:RU364152};
GN   Name=MED20 {ECO:0000256|RuleBase:RU364152};
GN   ORFNames=LADA_0E07228G {ECO:0000313|EMBL:SCU87950.1};
OS   Lachancea dasiensis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=1072105 {ECO:0000313|EMBL:SCU87950.1, ECO:0000313|Proteomes:UP000190274};
RN   [1] {ECO:0000313|Proteomes:UP000190274}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Devillers H.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC       the regulated transcription of nearly all RNA polymerase II-dependent
CC       genes. Mediator functions as a bridge to convey information from gene-
CC       specific regulatory proteins to the basal RNA polymerase II
CC       transcription machinery. Mediator is recruited to promoters by direct
CC       interactions with regulatory proteins and serves as a scaffold for the
CC       assembly of a functional preinitiation complex with RNA polymerase II
CC       and the general transcription factors. {ECO:0000256|RuleBase:RU364152}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364152}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU364152}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 20 family.
CC       {ECO:0000256|ARBA:ARBA00010743, ECO:0000256|RuleBase:RU364152}.
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DR   EMBL; LT598455; SCU87950.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G4JCR1; -.
DR   STRING; 1266660.A0A1G4JCR1; -.
DR   OrthoDB; 2041863at2759; -.
DR   Proteomes; UP000190274; Chromosome E.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 3.30.310.180; -; 2.
DR   InterPro; IPR013921; Mediator_Med20.
DR   Pfam; PF08612; Med20; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364152};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364152};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190274};
KW   Transcription {ECO:0000256|RuleBase:RU364152};
KW   Transcription regulation {ECO:0000256|RuleBase:RU364152}.
SQ   SEQUENCE   212 AA;  24029 MW;  41EEF238015914E2 CRC64;
     MHSTIIFVER SAPATITAFH DILSNELISI KEKWSFEFKT FRLTVKNLLP DSTRLMHSIT
     LSHMENKSVI VKNKSAIVTS VAQGGLLEGL TLNGCSSGVC ESFDNLLASK LSNLWTQRQS
     IKGDFGSTYQ TTELVIRATN VFSYGGFKGL LIEIICEDDV SDQEFEQRVS KIRNYLKEIS
     IEDYKICGDF MNPQKRDFIC DLAHQYIRVL EL
//