ID   A0A1G4JS68_9SACH        Unreviewed;       127 AA.
AC   A0A1G4JS68;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   13-SEP-2023, entry version 17.
DE   RecName: Full=Mitochondrial pyruvate carrier {ECO:0000256|RuleBase:RU363100};
GN   ORFNames=LANO_0E04522G {ECO:0000313|EMBL:SCU93681.1};
OS   Lachancea nothofagi CBS 11611.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=1266666 {ECO:0000313|EMBL:SCU93681.1};
RN   [1] {ECO:0000313|EMBL:SCU93681.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 11611 {ECO:0000313|EMBL:SCU93681.1};
RA   Devillers H.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the uptake of pyruvate into mitochondria.
CC       {ECO:0000256|RuleBase:RU363100}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC       inner membrane {ECO:0000256|ARBA:ARBA00004448,
CC       ECO:0000256|RuleBase:RU363100}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU363100}.
CC   -!- SIMILARITY: Belongs to the mitochondrial pyruvate carrier (MPC) (TC
CC       2.A.105) family. {ECO:0000256|ARBA:ARBA00006416,
CC       ECO:0000256|RuleBase:RU363100}.
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DR   EMBL; LT598451; SCU93681.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G4JS68; -.
DR   OrthoDB; 3375631at2759; -.
DR   Proteomes; UP000189911; Chromosome e.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006850; P:mitochondrial pyruvate transmembrane transport; IEA:InterPro.
DR   InterPro; IPR005336; MPC.
DR   PANTHER; PTHR14154:SF3; MITOCHONDRIAL PYRUVATE CARRIER; 1.
DR   PANTHER; PTHR14154; UPF0041 BRAIN PROTEIN 44-RELATED; 1.
DR   Pfam; PF03650; MPC; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363100};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW   ECO:0000256|RuleBase:RU363100};
KW   Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792,
KW   ECO:0000256|RuleBase:RU363100};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363100};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363100};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363100}.
FT   TRANSMEM        25..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363100"
FT   TRANSMEM        58..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363100"
SQ   SEQUENCE   127 AA;  14222 MW;  B7E9772F7963FD88 CRC64;
     MSQSAQKAAT QSILRRYVNK ETMKYVFTTH FWGPVSNFGI PLAAIYDLKK DPEMISGPMT
     GALIMYSAVF MKFALTVQPR NFLLFGCHVV NEFAQTGQAF RFVNYHYLGG NENKVKEAAT
     SAVAKPE
//