ID A0A1G4K3J0_9SACH Unreviewed; 541 AA.
AC A0A1G4K3J0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN ORFNames=LAMI_0F13762G {ECO:0000313|EMBL:SCU98256.1};
OS Lachancea mirantina.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=1230905 {ECO:0000313|EMBL:SCU98256.1, ECO:0000313|Proteomes:UP000191024};
RN [1] {ECO:0000313|Proteomes:UP000191024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Devillers H.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
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DR EMBL; LT598467; SCU98256.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G4K3J0; -.
DR STRING; 1230905.A0A1G4K3J0; -.
DR OrthoDB; 916229at2759; -.
DR Proteomes; UP000191024; Chromosome f.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032413; Arm_3.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR036975; Importin-a_IBB_sf.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF71; IMPORTIN SUBUNIT ALPHA; 1.
DR Pfam; PF00514; Arm; 8.
DR Pfam; PF16186; Arm_3; 1.
DR Pfam; PF01749; IBB; 1.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 8.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 2.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005673};
KW Reference proteome {ECO:0000313|Proteomes:UP000191024};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
FT DOMAIN 1..64
FT /note="IBB"
FT /evidence="ECO:0000259|PROSITE:PS51214"
FT REPEAT 129..172
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 172..200
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 541 AA; 59767 MW; C5954312521B5146 CRC64;
MDADSGSSNK FVPEYRRTNF KNKGRFSADE LRRRRDTQQV ELRKAKRDEA LAKRRNFAVA
AAGPDSEDED EAASSADQQF YQQLQVELPQ MVQQINATDL QEQLAATVKF RQILSREHRP
PIDTVIQSGV VPNLVNFMNE NQPEMLQLEA AWALTNIASG TSDQTKVVVE AGAVPLFIQL
LYTGSVEVKE QAIWALGNVA GDSTGYRDYV LGCGAMQPIL ALFNLNKNSL IRTATWTLSN
LCRGKKPQPD WAIVSQALPT LAKLIYSMDT ETLVDACWAI SYLSDGTAEA IQAVVDVRIP
KRLVELLNHQ STLVQTPALR AVGNIVTGTD LQTQVVINSG VLGALRNLLG SPKESIRKEA
CWTVSNITAG NTDQIQAVID SNLVPPLIRL LETADYKTKK EACWAISNAS SGGLQKPDII
RYLVSQGCIK PLCDLLEIAD NRIIEVTLDA LENILKMGEA DKEARGLHIN ENADYIEKAG
GMEKIFNCQQ NENEKIYEKA FNIIEQYFSE EDDAVDESMA PQTAGNTFGF GSSVNQQFNF
N
//
