ID A0A1G4KBD1_9SACH Unreviewed; 341 AA.
AC A0A1G4KBD1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=High osmolarity signaling protein SHO1 {ECO:0000256|ARBA:ARBA00017350};
DE AltName: Full=High osmolarity signaling protein sho1 {ECO:0000256|ARBA:ARBA00016255};
DE AltName: Full=Osmosensor SHO1 {ECO:0000256|ARBA:ARBA00029697, ECO:0000256|ARBA:ARBA00030785};
GN ORFNames=LANO_0F11980G {ECO:0000313|EMBL:SCV01481.1};
OS Lachancea nothofagi CBS 11611.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=1266666 {ECO:0000313|EMBL:SCV01481.1};
RN [1] {ECO:0000313|EMBL:SCV01481.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 11611 {ECO:0000313|EMBL:SCV01481.1};
RA Devillers H.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SHO1 family.
CC {ECO:0000256|ARBA:ARBA00009739}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LT598452; SCV01481.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G4KBD1; -.
DR OrthoDB; 1365981at2759; -.
DR Proteomes; UP000189911; Chromosome f.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd11855; SH3_Sho1p; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035522; Sho1_SH3.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR PANTHER; PTHR15735:SF20; PROTEIN NERVOUS WRECK; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 277..338
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
SQ SEQUENCE 341 AA; 37633 MW; 134E2E91B13A7967 CRC64;
MAIPNRTEAK QMRSNPHRIH EFKIANLLTD PFAISLLSLA LISWIIAFVG SVTAASNSSK
YPPFAWWGIA YQFLLLVIIF FLYCYELIDY YRSFLAGALA VAFIYTTNST GDLIYLDGSR
MGAASAGLIL LSMINAIWLF YFGADNASPS NRWIDSYSLK GIRHSVFESS IALSSRPTMA
GRNVSKYSAT PHDAPYSEQL PHSTSFYPDT HSQHYVSSTA LNGFENAEPP AAPALQNNLP
NTQNSNTFFT DTTNGNTETT MGDTLGLYSD AGDELGSFPY VAKALYTYSA DSNDAYEVSF
EQGETLRVGD IEGRWWKAKR ANGQTGIIPS NYVELISESS F
//
