ID A0A1G4KG69_9SACH Unreviewed; 207 AA.
AC A0A1G4KG69;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=DNA replication complex GINS protein PSF1 {ECO:0000256|ARBA:ARBA00015143, ECO:0000256|RuleBase:RU368085};
GN ORFNames=LAMI_0H08064G {ECO:0000313|EMBL:SCV03427.1};
OS Lachancea mirantina.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=1230905 {ECO:0000313|EMBL:SCV03427.1, ECO:0000313|Proteomes:UP000191024};
RN [1] {ECO:0000313|Proteomes:UP000191024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Devillers H.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for correct functioning of the GINS complex, a
CC complex that plays an essential role in the initiation of DNA
CC replication, and progression of DNA replication forks. GINS complex
CC seems to bind preferentially to single-stranded DNA.
CC {ECO:0000256|RuleBase:RU368085}.
CC -!- SUBUNIT: Component of the GINS complex.
CC {ECO:0000256|RuleBase:RU368085}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU368085}.
CC -!- SIMILARITY: Belongs to the GINS1/PSF1 family.
CC {ECO:0000256|ARBA:ARBA00006677, ECO:0000256|RuleBase:RU368085}.
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DR EMBL; LT598468; SCV03427.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G4KG69; -.
DR STRING; 1230905.A0A1G4KG69; -.
DR OrthoDB; 166901at2759; -.
DR Proteomes; UP000191024; Chromosome h.
DR GO; GO:0000811; C:GINS complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd11710; GINS_A_psf1; 1.
DR CDD; cd21696; GINS_B_Psf1; 1.
DR Gene3D; 1.20.58.1030; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR005339; GINS_Psf1.
DR PANTHER; PTHR12914:SF2; DNA REPLICATION COMPLEX GINS PROTEIN PSF1; 1.
DR PANTHER; PTHR12914; PARTNER OF SLD5; 1.
DR Pfam; PF05916; Sld5; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU368085};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU368085};
KW Reference proteome {ECO:0000313|Proteomes:UP000191024}.
FT DOMAIN 27..126
FT /note="GINS subunit"
FT /evidence="ECO:0000259|Pfam:PF05916"
FT COILED 6..63
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 207 AA; 23612 MW; 76FBDE94EAA0C2CE CRC64;
MYGDLVNKLV LEAKRAQQLN ESSKSEHLPM YQDDLVRNTL REIEQLKRDA ELLKSQQELN
QVEDKVARCQ HFVTLLCMER NKRGLLAYQK LRSDTLDAMA WNKHGLDSVT ALAAGEGADA
SLSHQEEEYL KDYTQIIADM KSGEFTDIDL SGSLTPPSDV FIDVRVLKDA GEIQTEYGVF
NLIKDSQFFA RQADVERLIQ QGFLQRL
//
