ID   A0A1G4MFY9_LACFM        Unreviewed;       461 AA.
AC   A0A1G4MFY9;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=asparagine--tRNA ligase {ECO:0000256|ARBA:ARBA00012816};
DE            EC=6.1.1.22 {ECO:0000256|ARBA:ARBA00012816};
GN   ORFNames=LAFE_0F11672G {ECO:0000313|EMBL:SCW02667.1};
OS   Lachancea fermentati (Zygosaccharomyces fermentati).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=4955 {ECO:0000313|EMBL:SCW02667.1, ECO:0000313|Proteomes:UP000190831};
RN   [1] {ECO:0000313|Proteomes:UP000190831}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Devillers H.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT598490; SCW02667.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G4MFY9; -.
DR   STRING; 4955.A0A1G4MFY9; -.
DR   OMA; DNMDLAE; -.
DR   OrthoDB; 2786597at2759; -.
DR   Proteomes; UP000190831; Chromosome f.
DR   GO; GO:0004816; F:asparagine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006421; P:asparaginyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd00776; AsxRS_core; 1.
DR   CDD; cd04318; EcAsnRS_like_N; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR004364; Aa-tRNA-synt_II.
DR   InterPro; IPR006195; aa-tRNA-synth_II.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR004522; Asn-tRNA-ligase.
DR   InterPro; IPR002312; Asp/Asn-tRNA-synth_IIb.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR004365; NA-bd_OB_tRNA.
DR   NCBIfam; TIGR00457; asnS; 1.
DR   PANTHER; PTHR22594:SF34; ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED; 1.
DR   PANTHER; PTHR22594; ASPARTYL/LYSYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF00152; tRNA-synt_2; 1.
DR   Pfam; PF01336; tRNA_anti-codon; 1.
DR   PRINTS; PR01042; TRNASYNTHASP.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE   4: Predicted;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190831}.
FT   DOMAIN          137..450
FT                   /note="Aminoacyl-transfer RNA synthetases class-II family
FT                   profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50862"
SQ   SEQUENCE   461 AA;  53018 MW;  7242E8B8B2D72E90 CRC64;
     MSLPPTVKSL FKLISNPPLC VNNLHGWVKS VRLLKKVAFI DLQDGTTSKP IKLVIPREAN
     DCLKQLRTGQ SLHIKKANWK QTPSREQSFE LEALPQSVRI IGDVPDTYPL QKKYHSLSFL
     RSLPTLKHRS NYLGALLRFR SHVENSFASF FESQDFTKVS PPILTSSDCE GAGELFRVES
     NSKIASKELY FGKPTYLTVS TQLHLEIMAM ALSRCWTLSP SFRAEESDTN RHLAEFWMLE
     AELCFIDDVR KLSKFTESML KYVIRSCLQN KDSLLPAMVP QENTESLDNI AQRWEAMLLK
     EWPILSYTET IKLLQERHKK VAFKFPPSWG NALQTEHEKW LADSYNSPVF VVDYPRECKA
     FYMKQNNDDT VACFDLLVPQ MGEIIGGSIR EDDYERILQE MERRKMNTKD LEWYTSLRKQ
     GSAPHGGFGL GLERFVSWMF GSQNVRDAIP FHRSADGVID L
//