ID A0A1G4MKL6_LACFM Unreviewed; 238 AA.
AC A0A1G4MKL6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Ribosome assembly factor mrt4 {ECO:0000256|RuleBase:RU364039};
GN ORFNames=LAFE_0H13674G {ECO:0000313|EMBL:SCW04445.1};
OS Lachancea fermentati (Zygosaccharomyces fermentati).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=4955 {ECO:0000313|EMBL:SCW04445.1, ECO:0000313|Proteomes:UP000190831};
RN [1] {ECO:0000313|EMBL:SCW04445.1, ECO:0000313|Proteomes:UP000190831}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 6772 {ECO:0000313|EMBL:SCW04445.1};
RA Devillers H.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the ribosome assembly machinery. Nuclear paralog
CC of the ribosomal protein P0, it binds pre-60S subunits at an early
CC stage of assembly in the nucleolus, and is replaced by P0 in
CC cytoplasmic pre-60S subunits and mature 80S ribosomes.
CC {ECO:0000256|ARBA:ARBA00004046, ECO:0000256|RuleBase:RU364039}.
CC -!- SUBUNIT: Associates with the pre-60S ribosomal particle.
CC {ECO:0000256|ARBA:ARBA00011117, ECO:0000256|RuleBase:RU364039}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU364039}.
CC Nucleus, nucleolus {ECO:0000256|RuleBase:RU364039}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC {ECO:0000256|ARBA:ARBA00008889, ECO:0000256|RuleBase:RU364039}.
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DR EMBL; LT598491; SCW04445.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G4MKL6; -.
DR STRING; 4955.A0A1G4MKL6; -.
DR OMA; LEWAENY; -.
DR OrthoDB; 23333at2759; -.
DR Proteomes; UP000190831; Chromosome h.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR CDD; cd05796; Ribosomal_P0_like; 1.
DR Gene3D; 3.30.70.1730; -; 1.
DR Gene3D; 3.90.105.20; -; 1.
DR InterPro; IPR033867; Mrt4.
DR InterPro; IPR001790; Ribosomal_uL10.
DR InterPro; IPR040637; Ribosomal_uL10-like_insert.
DR InterPro; IPR043164; Ribosomal_uL10-like_insert_sf.
DR InterPro; IPR043141; Ribosomal_uL10-like_sf.
DR PANTHER; PTHR45841:SF1; MRNA TURNOVER PROTEIN 4 HOMOLOG; 1.
DR PANTHER; PTHR45841; MRNA TURNOVER PROTEIN 4 MRTO4; 1.
DR Pfam; PF00466; Ribosomal_L10; 1.
DR Pfam; PF17777; RL10P_insert; 1.
DR SUPFAM; SSF160369; Ribosomal protein L10-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU364039};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364039};
KW Reference proteome {ECO:0000313|Proteomes:UP000190831};
KW Ribosome biogenesis {ECO:0000256|RuleBase:RU364039}.
FT DOMAIN 130..208
FT /note="Large ribosomal subunit protein uL10-like insertion"
FT /evidence="ECO:0000259|Pfam:PF17777"
SQ SEQUENCE 238 AA; 27122 MW; EF890B5CDE2C3F64 CRC64;
MPRSKRSKLV TLAQTDKKGR ENKERIFDEV REALDSFRYV WVLHLDNVRT PVLQEIRTAW
NGSKLIMGKR KVLEKALGMK REDEYKENLS KLTKHCSGVT GLLFTNEDTQ TVEDYFRSYV
RSDYSRPKSK APLTFELPAG IIYSRGGQIP PEEDVPMVHS LEPTMRNKFK IPTKIKGGKI
TIESPYLVCE KGQTLDVRQA LILKQFGVAA AEFRVKATAY YDNEASTVEE VGINTESA
//
