ID A0A1G4TQQ1_9CAUL Unreviewed; 777 AA.
AC A0A1G4TQQ1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=EAL domain, c-di-GMP-specific phosphodiesterase class I (Or its enzymatically inactive variant) {ECO:0000313|EMBL:SCW83650.1};
GN ORFNames=SAMN02927928_0087 {ECO:0000313|EMBL:SCW83650.1};
OS Asticcacaulis taihuensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Asticcacaulis.
OX NCBI_TaxID=260084 {ECO:0000313|EMBL:SCW83650.1, ECO:0000313|Proteomes:UP000199150};
RN [1] {ECO:0000313|EMBL:SCW83650.1, ECO:0000313|Proteomes:UP000199150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.3431 {ECO:0000313|EMBL:SCW83650.1,
RC ECO:0000313|Proteomes:UP000199150};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FMTS01000011; SCW83650.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1G4TQQ1; -.
DR STRING; 260084.SAMN02927928_0087; -.
DR Proteomes; UP000199150; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR029150; dCache_3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF14827; dCache_3; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 260..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 284..335
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 369..500
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 509..759
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 777 AA; 84583 MW; 2C944E75B596C590 CRC64;
MFGGLFALAL LLIALASYMA VVSYARASVQ KELQASASVF KRIWTLKSDA LQTNAVLLSR
DFGFKSALAT HDTATVESAF DNLQGRLNIE TGLIIGRDGQ PMAGEQGSLG QTLAGALSRK
DEFGAVNGII AIDTHPYQAV AAPVMAPDRL GWVVFAQRLD DNEMQNLQGL SSIPIKAGIL
TQTRGGLWLG PQEQTRDYKP SSLSFFIDKS LQTKAASMVH SSRGTMIAVA TPLPNLDSQQ
KSVLLLSYPL SSALKSYQPL LTALLAIGLF GLCMVVAASL YLARNLTRPI LALKDAAFAL
RDGRPGQVRI TTQDEMADLA SAFNDMAVSI EDRERDITLL AKSDMATGLP NRSAFEDYIG
GLRDKGIDSG VVVVCIGIDR YAHIRAVWGV SYAHTLIARL QDILVRIFAN AYIARLSADT
LGLCLHPCEV DQALPLARAI AARLDKRIKV TEDQSLDVMV SLGVYHMANA RPTPDEMIER
ALIALDQARA AKTRIALFDP RIYSELADTL LLTDQLYAAL ASKALQVWYQ PKFSYRESRI
ISVEALVRWN HAERGYVSPQ RFVQIAEETG AIRDLTTQVL HTCIADQGRL KSAGFDLDIS
INYSGRLLSD EAYNAHALNI CDQAVGQICL EITETAVIED PRIGLAAINT FVDRGLEISI
DDFGTGLSSL AYLKQIPAHE LKIDRSFIME IESGQRDALL VRSAIDLAHG LGMKVTAEGV
ETAAAFTLLQ SMGCDIAQGY GIGKPMPFGD LILFLNDFSG MSETKTQMPT YRNRKAV
//
