ID   A0A1G4VVF7_9FIRM        Unreviewed;      1019 AA.
AC   A0A1G4VVF7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=PQQ-like domain-containing protein {ECO:0000313|EMBL:SCX12501.1};
GN   ORFNames=SAMN02910339_01749 {ECO:0000313|EMBL:SCX12501.1};
OS   Lachnospiraceae bacterium YSD2013.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1520828 {ECO:0000313|EMBL:SCX12501.1, ECO:0000313|Proteomes:UP000199278};
RN   [1] {ECO:0000313|EMBL:SCX12501.1, ECO:0000313|Proteomes:UP000199278}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YSD2013 {ECO:0000313|EMBL:SCX12501.1,
RC   ECO:0000313|Proteomes:UP000199278};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FMTX01000015; SCX12501.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1G4VVF7; -.
DR   STRING; 1520828.SAMN02910339_01749; -.
DR   OrthoDB; 89550at2; -.
DR   Proteomes; UP000199278; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR002372; PQQ_repeat.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR47197:SF3; PE-PGRS FAMILY PROTEIN PE_PGRS17; 1.
DR   PANTHER; PTHR47197; PROTEIN NIRF; 1.
DR   Pfam; PF13360; PQQ_2; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199278};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..157
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   1019 AA;  113890 MW;  52693B20B51B5370 CRC64;
     MKYNAFISYR HAPLDMEIAK KVHTGLETYK IPKSVQKRLG IKKIERVFRD QEELPIGSNL
     SDNIGEALKE SEHLIVICSP RTPESEWVQK EIETFIKLHG RENVLAVLVE GEPNESFPEL
     LLNDENGNPV EPLAADVRGE TASERNKKFK TEILRLVAPV IGCNYDDLRQ RHRERIVRRT
     VSLVSAAAGI IAIAGIAFGL YHANVADKMT TLANEKAQLA DEKTQLADEI LEEYKLKQEN
     QSRFFAKEAL SLMNEGNRED AALVAIAGLP GPGNERPYVP EAEYALSQVL HAYDTGEEMA
     FDRILEHDLT PLDEKLSTDK KHLLTRDNGY NVYVWDAETW ELVCKISPAV GKNNYLVKVD
     DFFADADGLY ILSDYSLDKY SFTGEKLFSF ESDSYIDGAT ISAERNTGYL LIDNSVVSLD
     LSKGKEISTI EFPVEGSVYS QIDISRDEEY LLFTYRKADT ERIDIAAYNI DKNTFNLTRL
     SDDYVLEYAY TALGNLAVLS CNQDFVMTGV KTIYLDLINP QTGNIMWTRE VPCSIRSNAT
     FDLKIKAHSY DTAAGETFSE IVIAVEAEAF TYNELTSKLV ASMNLPGDTV TLDLRRDNAV
     GFVSDDNGRI YTVNFHEGTI YKDNTFDVNS SIRQIIIMDG VIAIRSAYSS AIQIMKYHTA
     GDLTEIADYV DYFTTLKTAP LGSDYFVTRR DKADSYLVIS KDGKLIAEAQ LDSTYTILDG
     FRGDNVLLFS YETMYTIDTS TGKIDSISYE KLGSSDSKLF HGYLSENGRY AVLWDNRHIT
     VIDTEQKKML LDSDGTASIN NAVVTEDGKS VFVSASDMNL IKIDVATKNE TLYDNDALRE
     VSDAYSLNFV AVSHDGKTVA MACMDGKLRI LNAADGKTID EVPFYARSHC AIFFAPDDKN
     LILQGDDLKA SIRNIEDKTY TNSFDPVFEL KRPTCAGDGY LAVCDATCLY LLETNSYGVC
     ASVTYGGAYI PSEKSFIIAS SGKLYKTAYK DYKALIEEAE RQFPGAALTE EEKVKYNIN
//