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Database: UniProt
Entry: A0A1G4W0B9_9FIRM
LinkDB: A0A1G4W0B9_9FIRM
Original site: A0A1G4W0B9_9FIRM 
ID   A0A1G4W0B9_9FIRM        Unreviewed;       790 AA.
AC   A0A1G4W0B9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   11-DEC-2019, entry version 8.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=SAMN02910339_02043 {ECO:0000313|EMBL:SCX14739.1};
OS   Lachnospiraceae bacterium YSD2013.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Lachnospiraceae.
OX   NCBI_TaxID=1520828 {ECO:0000313|EMBL:SCX14739.1, ECO:0000313|Proteomes:UP000199278};
RN   [1] {ECO:0000313|EMBL:SCX14739.1, ECO:0000313|Proteomes:UP000199278}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YSD2013 {ECO:0000313|EMBL:SCX14739.1,
RC   ECO:0000313|Proteomes:UP000199278};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake system.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
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DR   EMBL; FMTX01000018; SCX14739.1; -; Genomic_DNA.
DR   Proteomes; UP000199278; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   Gene3D; 2.30.30.90; -; 1.
DR   InterPro; IPR007167; Fe-transptr_FeoA.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR038157; FeoA_core_dom.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR008988; Transcriptional_repressor_C.
DR   Pfam; PF04023; FeoA; 1.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SMART; SM00899; FeoA; 1.
DR   SUPFAM; SSF50037; SSF50037; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199278};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM        412..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        468..494
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        523..541
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        553..576
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        582..603
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        641..660
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        700..720
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        726..752
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        764..785
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   DOMAIN          124..285
FT                   /note="FeoB-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51711"
FT   REGION          81..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        100..114
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   790 AA;  86653 MW;  8937D7D57E848D1A CRC64;
     MTLKELPIGQ SATVKVVGGS GSLRQHFLDM GLIPGVEVTV MKLAPLGDPM ELMIHGYELT
     LRLADAEQIE VDEESAHTYV KPENQPEKPK GVLTLKNHTD HPGLGEEGRY HSKADENPLP
     EGTLLTFALA GNQNCGKTTL FNQLTGANRH VGNFPGVTVD RISGAIKGRP GTEVTDLPGI
     YSLSPYTSEE IVSRQFIINE KPTGIINIVD ATNIERNLYL TMQLMELDVP MVLALNMMDE
     VRGNGGHIRV NDLEEALGIP VVPISASKNE GVQELVEHAV HIAKYCERPG RKDFCDKEDH
     GGAVHRCLHG IMHLIEDKAT AAGIPVRFAA SKLVEGDSLI KKALKLAPDE AGMVEQIIRR
     MEKERGLDRQ AAIADMRFSF IGKLCDKAVV KPAESKEHER SRKIDRLLTG KYTAIPIFVL
     IMALVFYLTF NVIGAWMQDG LQFLIESLAG VVGDAFERWN VNGTVQSLVI DAIFGGVGSV
     VSFVPIIVTL FFFLSMLEDS GYMARVAFVM DKLLRKLGLS GRSIVPMLIG FGCTVPGVMA
     ARTLPSERDR RMTILLTPFM SCSAKLPIYG FFATLFFPNC AWLVMVALYV LGILVGIVTA
     FLFKKTVFKG EPVPFVMELP NYRIPGAKNV LHLLWDKARD FLQRAFTIIF VATIVVWLLQ
     TFDFTLTAVA DPSDSILATI AGFIAPIFKP LGFNDYRFST ALITGFMAKE SVVSTLLVLF
     GSETAMLAAM TTVSAAALLT FCLLYTPCVA AVASVKRELG RKYALFMVLF QCAVAWICGM
     LVNVIGNMIF
//
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